Abstract
Here we present an overview of what is known about endogenous plant compounds that act as inhibitors of hormonal transport processes in plants, about their identity and mechanism of action. We have also summarized commonly and less commonly used compounds of non-plant origin and synthetic drugs that show at least partial ‘specificity’ to transport or transporters of particular phytohormones. Our main attention is focused on the inhibitors of auxin transport. The urgent need to understand precisely the molecular mechanism of action of these inhibitors is highlighted.
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Abbreviations
- ABA:
-
Abscisic acid
- ABCB:
-
ATP-binding cassette subfamily B
- ABCG:
-
ATP-binding cassette subfamily G
- ARF:
-
ADP-ribosylation factor
- ARF:
-
Auxin response factor
- ARF-GAP:
-
ARF-GTPase-activating protein
- ARF/GEF:
-
ADP-ribosylation factor/GTPase guanine-nucleotide exchange factor
- AtVPS45:
-
Vacuolar protein sorting 45
- AUX1:
-
Auxin resistant 1
- BEN:
-
BFA-visualized endocytic trafficking defective
- bex :
-
BFA- visualized exocytic trafficking defective
- BFA:
-
Brefeldin A
- CCCP:
-
m-Chlorophenyl hydrazone
- CHPAA:
-
3-Chloro-4-hydroxyphenylacetic acid
- CPD:
-
Cyclopropyl propane dione
- CSI:
-
Chromosaponin I
- CTPP:
-
COOH-terminal propeptide
- 2,4-D:
-
2,4-Dichlorophenoxyacetic acid
- ER:
-
Endoplasmic reticulum
- FCCP:
-
Carbonyl cyanide-4-(trifluoromethoxy)phenyl hydrazone
- GNL2:
-
GNOM-LIKE 2
- HFCA:
-
9-Hydroxyfluorene-9-carboxylic acid
- IAA:
-
Indole-3-acetic acid
- MDR:
-
Multidrug resistance
- MVBs:
-
Multivesicular bodies
- NAA:
-
Naphthalene-1-acetic acid
- 2-NAA:
-
Naphthalene-2-acetic acid
- NBP:
-
NPA-binding protein
- 1-NOA:
-
1-Naphthoxyacetic acid
- 2-NOA:
-
2-Naphthoxyacetic acid
- NPA:
-
1-Naphthylphthalamic acid
- OxIAA:
-
2-Oxindole-3-acetic acid
- PBA:
-
2-(1-Pyrenoyl)-benzoic acid
- PGP:
-
Phosphoglycoprotein
- PI3K:
-
Phosphatidylinositol-3-kinase
- PI4K:
-
Phosphatidylinositol-4-kinase
- PIN:
-
Pin-formed
- PM:
-
Plasma membrane
- PP2A:
-
Phosphatase 2A
- PVC:
-
Prevacuolar compartment
- RabA1b:
-
Ras genes from rat brain A1b
- ROS:
-
Reactive oxygen species
- SCF:
-
Scarface
- SEC8:
-
Secretory 8
- TGN/EE:
-
Trans-Golgi network/early endosome
- TIBA:
-
2,3,5-Triiodobenzoic acid
- TOL:
-
Target of MYB (TOM) 1-like
- trans-CA:
-
Trans-cinnamic acid
- tt4 :
-
Transparent testa4
- TWD1:
-
Twisted-dwarf-1
- VAN:
-
Vascular network defective
- VLCFAs:
-
Very long chain fatty acids
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The authors thank the Ministry of Education, Youth and Sports of the Czech Republic (project COST-CZ LD15088) for support of their work.
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Klíma, P., Laňková, M. & Zažímalová, E. Inhibitors of plant hormone transport. Protoplasma 253, 1391–1404 (2016). https://doi.org/10.1007/s00709-015-0897-z
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DOI: https://doi.org/10.1007/s00709-015-0897-z