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Microwave-assisted pseudo four-component synthesis of trans,trans-2-amino-1,3,3-tricyano-5-nitro-4,6-bis(aryl)cyclohexenes using α-Fe2O3 nanoparticles

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Abstract

This work described a simple and efficient synthesis of trans,trans-2-amino-1,3,3-tricyano-5-nitro-4,6-bis(aryl)cyclohexenes via a simple pseudo four-component reaction between (E)-(2-nitrovinyl)benzene and malononitrile in the presence of sodium carbonate and α-Fe2O3 nanoparticles. Eco-friendly, solvent-free condition, excellent product yield, short reaction time, inexpensive and readily available starting material are the main advantages of this method.

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Acknowledgements

I gratefully acknowledge the financial support from the Research Council of Payame Noor University (PNU), Tehran, Iran.

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Authors and Affiliations

  1. Department of Chemistry, Payame Noor University, P. O. Box 19395-3697, Tehran, Iran

    Bagher Mohammadi, Ezzat Ollah Najafi & Vahid Azizkhani

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  1. Bagher Mohammadi
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  2. Ezzat Ollah Najafi
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  3. Vahid Azizkhani
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Corresponding author

Correspondence to Bagher Mohammadi.

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Mohammadi, B., Najafi, E.O. & Azizkhani, V. Microwave-assisted pseudo four-component synthesis of trans,trans-2-amino-1,3,3-tricyano-5-nitro-4,6-bis(aryl)cyclohexenes using α-Fe2O3 nanoparticles. Monatsh Chem 148, 1095–1099 (2017). https://doi.org/10.1007/s00706-016-1890-8

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  • DOI: https://doi.org/10.1007/s00706-016-1890-8

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