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Total synthesis of racemic 1-aryl-tetrahydroisoquinoline alkaloids

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Abstract

A new synthetic route was developed for the preparation of natural products cryptostyline I, II, III and 1-phenyl-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline. The Liebeskind–Srogl palladium-catalyzed carbon–carbon cross-coupling protocol was used in the key step of the total synthesis.

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Authors and Affiliations

  1. Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, Hungary

    Péter Ábrányi-Balogh, Tamás Földesi & Mátyás Milen

Authors
  1. Péter Ábrányi-Balogh
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  2. Tamás Földesi
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  3. Mátyás Milen
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Correspondence to Mátyás Milen.

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Ábrányi-Balogh, P., Földesi, T. & Milen, M. Total synthesis of racemic 1-aryl-tetrahydroisoquinoline alkaloids. Monatsh Chem 146, 1907–1912 (2015). https://doi.org/10.1007/s00706-015-1564-y

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