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Eco-friendly synthesis of highly substituted functionalized oxazines by FeCl3/SiO2 nanoparticles

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Abstract

An efficient and modern method for the preparation of amidoalkyl naphthols in the presence of silica nanoparticle-supported ferric chloride under thermal solvent-free conditions is explained. The prepared amidoalkyl naphthols were converted to 1,3-oxazines by Vilsmeier reagent in the presence of FeCl3/SiO2 nanoparticles. This method provides a novel route to synthesis amidoalkyl naphthol and 1,3-oxazine derivatives in terms of good yields, short reaction times, and recyclable catalyst.

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Acknowledgments

The authors are grateful to Islamic Azad University, Qom Branch, for financial support of this work.

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Authors and Affiliations

  1. Department of Chemistry, Qom Branch, Islamic Azad University, Qom, Islamic Republic Iran

    Javad Safaei Ghomi

  2. Faculty of Chemistry, Department of Organic Chemistry, University of Kashan, Kashan, 51167, Islamic Republic Iran

    Safura Zahedi

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  1. Javad Safaei Ghomi
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  2. Safura Zahedi
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Correspondence to Javad Safaei Ghomi.

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Ghomi, J.S., Zahedi, S. Eco-friendly synthesis of highly substituted functionalized oxazines by FeCl3/SiO2 nanoparticles. Monatsh Chem 144, 687–693 (2013). https://doi.org/10.1007/s00706-012-0850-1

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  • DOI: https://doi.org/10.1007/s00706-012-0850-1

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