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4H,8H-Pyrano[2,3-f]chromene-4,8-diones as versatile precursors for the synthesis of 6-(1,2-oxazol-5-yl)-2H-chromene-2-ones

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Abstract

An efficient and versatile synthesis of 3-azolyl-6-(1,2-oxazol-5-yl)-2H-chromene-2-ones using a Knoevenagel reaction and subsequent cleavage with hydroxylamine hydrochloride is described.

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Acknowledgments

We thank Enamine Ltd for providing the 13C NMR spectra.

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Authors and Affiliations

  1. Department of Chemistry, Kyiv National Taras Shevchenko University, Volodymyrska Street 60, Kyiv, 01033, Ukraine

    Oleg A. Lozinski, Tatyana V. Shokol & Vladimir P. Khilya

Authors
  1. Oleg A. Lozinski
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  2. Tatyana V. Shokol
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  3. Vladimir P. Khilya
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Correspondence to Oleg A. Lozinski.

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Lozinski, O.A., Shokol, T.V. & Khilya, V.P. 4H,8H-Pyrano[2,3-f]chromene-4,8-diones as versatile precursors for the synthesis of 6-(1,2-oxazol-5-yl)-2H-chromene-2-ones. Monatsh Chem 144, 217–222 (2013). https://doi.org/10.1007/s00706-012-0844-z

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  • DOI: https://doi.org/10.1007/s00706-012-0844-z

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