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Role of surgery in multi-modality treatment for carcinomatous pleuritis in patients with non-small cell lung cancer

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Abstract

Objective

To evaluate the role of surgery in the treatment of the patients with non-small cell lung cancer with pleural dissemination.

Methods

The clinical records of 25 patients (mean age 69 years) diagnosed with carcinomatous pleuritis during a thoracotomy by pathological examination and followed by surgery between 1994 and 2012 were reviewed. The treatment modality, including surgery, the clinicopathologic characteristics and 5-year survival were analyzed.

Results

There were 16 adenocarcinomas, 6 squamous cell carcinomas and 3 large cell carcinomas. Surgery included resection of the main tumor by partial resection in 10 cases, segmentectomy in 2 cases, lobar resection in 12 cases and bilobectomy in 1 case. Intrathoracic irrigation was performed in 20 cases. The pathological N status was N0/N1/N2/Nx: 10/6/7/2. Fifteen patients received adjuvant therapy. The overall 5-year survival rate was 22.2 %. The 5-year survival rates of the N0, N1 and N2 groups were 36.0, 16.7 and 14.3 %, respectively (p = 0.0068). Nine patients lived more than 3 years including 5 in N0, 3 in N1 and 1 in N2.

Conclusions

Surgery should not be excluded from the multi-modality treatment of patients with carcinomatous pleuritis because there are some patients who could benefit from surgery especially if they are in N0 status.

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Acknowledgments

This study received no financial support from any funds or institutes.

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Authors and Affiliations

  1. Department of General Thoracic, Breast and Endocrine Surgery, Faculty of Medicine, Kagawa University, 1750-1 Miki-Cho, Kita-Gun, Kagawa, 761-0793, Japan

    Tetsuhiko Go, Noriyuki Misaki, Natsumi Matsuura, Sung Soo Chang, Shintarou Tarumi & Hiroyasu Yokomise

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  1. Tetsuhiko Go
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  2. Noriyuki Misaki
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  3. Natsumi Matsuura
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  4. Sung Soo Chang
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  5. Shintarou Tarumi
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  6. Hiroyasu Yokomise
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Correspondence to Tetsuhiko Go.

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Go, T., Misaki, N., Matsuura, N. et al. Role of surgery in multi-modality treatment for carcinomatous pleuritis in patients with non-small cell lung cancer. Surg Today 45, 197–202 (2015). https://doi.org/10.1007/s00595-014-0987-0

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  • DOI: https://doi.org/10.1007/s00595-014-0987-0

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