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A ventricular assist device as a bridge to recovery, decision making, or transplantation in patients with advanced cardiac failure

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Abstract

Despite many advances in the management of patients with heart failure, acute cardiogenic shock and progressive congestive heart failure remain serious problems with dismal prognoses. Both temporary and permanent mechanical support has been gaining wide clinical application in this patient population. Although mechanical circulatory support technology is rapidly evolving, this approach is associated with multiple issues such as the optimal duration of temporary support, ideal timing to bridge these patients to a long-term device, and selection of the right device for the right patient. The currently available devices are categorized into two major groups: temporary and long-term devices (including destination therapy). Heart failure is a dynamic condition, and the therapeutic approach may need to be modified depending on the patient’s condition. Furthermore, the patient’s preexisting morbidity, age, socioeconomic status, and family support are confounding factors that need to be considered when making such decisions. Clinical trials including prospective studies, as well as meticulous analysis of existing data, may help develop universal guidelines to select the right device. This manuscript will review the most widely used ventricular assist devices.

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References

  1. Koelling TM, Chen RS, Lubwama RN, L’Italien GJ, Eagle KA. The expanding national burden of heart failure in the United States: the influence of heart failure in women. Am Heart J. 2004;147(1):74–8.

    Article  CAS  PubMed  Google Scholar 

  2. Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, Ganiats TG, et al. ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation. 2005;112(12):e154–235.

    Article  PubMed  Google Scholar 

  3. Rosamond T, Wetzel LH, Lakkireddy D, Ferrell R, Tadros P. IntraCameral right coronary artery: detection by 64 slice coronary computed tomographic angiography and implications for radiofrequency ablation of atrial dysrhythmias. Pacing Clin Electrophysiol. 2007;30(12):1571–4.

    Article  PubMed  Google Scholar 

  4. Harper AM, Rosendale JD. The UNOS OPTN Waiting List and Donor Registry: 1988–1996. Clin. Transpl. 1996;1:69–90.

    Google Scholar 

  5. O’Connell JB, McCarthy PM, Sopko G, Filippatos GS, Pina IL, Konstam MA, et al. Mechanical circulatory support devices for acute heart failure syndromes: considerations for clinical trial design. Heart Fail Rev. 2009;14(2):101–12.

    Article  PubMed  Google Scholar 

  6. Aggarwal S, Pagani FD. Bridge to transplantation: current outcomes. J Cardiac Surg. 2010;25(4):455–61.

    Article  Google Scholar 

  7. Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW, Dembitsky W, et al. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345(20):1435–43.

    Article  CAS  PubMed  Google Scholar 

  8. John R, Liao K, Kamdar F, Eckman P, Boyle A, Colvin-Adams M. Effects on pre- and posttransplant pulmonary hemodynamics in patients with continuous-flow left ventricular assist devices. J Thorac Cardiovasc Surg. 2010;140(2):447–52.

    Article  PubMed  Google Scholar 

  9. Pagani FD, Miller LW, Russell SD, Aaronson KD, John R, Boyle AJ, et al. Extended mechanical circulatory support with a continuous-flow rotary left ventricular assist device. J Am Coll Cardiol. 2009;54(4):312–21.

    Article  PubMed  Google Scholar 

  10. Dembitsky WP. REMATCH and beyond: the cost of treating heart failure using an implantable left ventricular assist device. Semin Cardiothorac Vasc Anesth. 2006;10(3):253–5.

    Article  PubMed  Google Scholar 

  11. Miller LW, Pagani FD, Russell SD, John R, Boyle AJ, Aaronson KD, et al. Use of a continuous-flow device in patients awaiting heart transplantation. N Engl J Med. 2007;357(9):885–96.

    Article  CAS  PubMed  Google Scholar 

  12. Aaronson KD, Patel H, Pagani FD. Patient selection for left ventricular assist device therapy. Ann Thorac Surg. 2003;75(6 Suppl):S29–35.

    Article  PubMed  Google Scholar 

  13. Hochman JS, Sleeper LA, Webb JG, Sanborn TA, White HD, Talley JD, et al. Early revascularization in acute myocardial infarction complicated by cardiogenic shock. SHOCK Investigators. Should we emergently revascularize occluded coronaries for cardiogenic shock. N Engl J Med. 1999;341(9):625–34.

    Article  CAS  PubMed  Google Scholar 

  14. Urban P, Stauffer JC, Bleed D, Khatchatrian N, Amann W, Bertel O, et al. A randomized evaluation of early revascularization to treat shock complicating acute myocardial infarction. The (Swiss) Multicenter Trial of Angioplasty for Shock-(S)MASH. Eur Heart J. 1999;20(14):1030–8.

    Article  CAS  PubMed  Google Scholar 

  15. Pagani FD, Lynch W, Swaniker F, Dyke DB, Bartlett R, Koelling T, et al. Extracorporeal life support to left ventricular assist device bridge to heart transplant: a strategy to optimize survival and resource utilization. Circulation. 1999;100(19 Suppl):II206–10.

    CAS  PubMed  Google Scholar 

  16. Chen JM, Weinberg AD, Rose EA, Thompson SM, Mancini DM, Ellison JP, et al. Multivariate analysis of factors affecting waiting time to heart transplantation. Ann Thorac Surg. 1996;61(2):570–5.

    Article  CAS  PubMed  Google Scholar 

  17. Lowy R, John R, Boyle A, et al. The use of the Levitronix VAS and long-term mechanical support to enhance patient outcome following cardiogenic shock. STS presentation. January 2009.

  18. Arabia FA, Smith RG, Rose DS, Arzouman DA, Sethi GK, Copeland JG. Success rates of long-term circulatory assist devices used currently for bridge to heart transplantation. ASAIO J. 1996;42(5):M542–6.

    Article  CAS  PubMed  Google Scholar 

  19. Smedira NG, Hoercher KJ, Yoon DY, Rajeswaran J, Klingman L, Starling RC, et al. Bridge to transplant experience: factors influencing survival to and after cardiac transplant. J Thorac Cardiovasc Surg. 139(5):1295–305, 305e1–e4.

  20. Deng MC, Edwards LB, Hertz MI, Rowe AW, Keck BM, Kormos R, et al. Mechanical circulatory support device database of the International Society for Heart and Lung Transplantation: second annual report—2004. J Heart Lung Transplant. 2004;23(9):1027–34.

    Article  PubMed  Google Scholar 

  21. John R, Pagani FD, Naka Y, Boyle A, Conte JV, Russell SD, et al. Post-cardiac transplant survival after support with a continuous-flow left ventricular assist device: impact of duration of left ventricular assist device support and other variables. J Thorac Cardiovasc Surg. 2010;140(1):174–81.

    Article  PubMed  Google Scholar 

  22. Fitzpatrick JR 3rd, Frederick JR, Hiesinger W, Hsu VM, McCormick RC, Kozin ED, et al. Early planned institution of biventricular mechanical circulatory support results in improved outcomes compared with delayed conversion of a left ventricular assist device to a biventricular assist device. J Thorac Cardiovasc Surg. 2009;137(4):971–7.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Pagani FD, Aaronson KD, Swaniker F, Bartlett RH. The use of extracorporeal life support in adult patients with primary cardiac failure as a bridge to implantable left ventricular assist device. Ann Thorac Surg. 2001;71(3 Suppl):S77–81. (discussion S2–5).

    Article  CAS  PubMed  Google Scholar 

  24. John R, Long JW, Massey HT, Griffith BP, Sun BC, Tector AJ, et al. Outcomes of a multicenter trial of the Levitronix CentriMag ventricular assist system for short-term circulatory support. J Thorac Cardiovasc Surg. 2011;141(4):932–9.

    Article  PubMed  Google Scholar 

  25. Vranckx P, Meliga E, De Jaegere PP, Van den Ent M, Regar ES, Serruys PW. The TandemHeart, percutaneous transseptal left ventricular assist device: a safeguard in high-risk percutaneous coronary interventions. The six-year Rotterdam experience. EuroIntervention. 2008;4(3):331–7.

    Article  PubMed  Google Scholar 

  26. Gregoric ID, Jacob LP, La Francesca S, Bruckner BA, Cohn WE, Loyalka P, et al. The TandemHeart as a bridge to a long-term axial-flow left ventricular assist device (bridge to bridge). Tex Heart Inst J Tex Heart Inst St. 2008;35(2):125–9.

    Google Scholar 

  27. Bruckner BA, Jacob LP, Gregoric ID, Loyalka P, Kar B, Cohn WE, et al. Clinical experience with the TandemHeart percutaneous ventricular assist device as a bridge to cardiac transplantation. Tex Heart Inst J Tex Heart Inst St. 2008;35(4):447–50.

    Google Scholar 

  28. Cheng JM, den Uil CA, Hoeks SE, van der Ent M, Jewbali LS, van Domburg RT, et al. Percutaneous left ventricular assist devices vs. intra-aortic balloon pump counterpulsation for treatment of cardiogenic shock: a meta-analysis of controlled trials. Eur Heart J. 2009;30(17):2102–8.

    Article  PubMed  Google Scholar 

  29. Reverdin S, Gregoric ID, Kar B, Loyalka P, Bieniarz MC, LeMaire SA, et al. Bridge to transplantation with the TandemHeart: bending the indications in a chronic aortic dissection patient with postcardiotomy shock. Tex Heart Inst J Tex Heart Inst St. 2008;35(3):340–1.

    Google Scholar 

  30. Kar B, Adkins LE, Civitello AB, Loyalka P, Palanichamy N, Gemmato CJ, et al. Clinical experience with the TandemHeart percutaneous ventricular assist device. Tex Heart Inst J Tex Heart Inst St. 2006;33(2):111–5.

    Google Scholar 

  31. Kar B, Forrester M, Gemmato C, Civitello A, Loyalka P, Myers T, et al. Use of the TandemHeart percutaneous ventricular assist device to support patients undergoing high-risk percutaneous coronary intervention. J Invasive Cardiol. 2006;18(4):A6.

    PubMed  Google Scholar 

  32. Gregoric ID, Bruckner BA, Jacob L, Loyalka P, Kar B, La Francesca S, et al. Techniques and complications of TandemHeart ventricular assist device insertion during cardiac procedures. ASAIO J. 2009;55(3):251–4.

    Article  PubMed  Google Scholar 

  33. Luo XJ, Hu SS, Sun HS, Xu JP, Liu P, Zheng Z, et al. Clinical application of BVS5000 left ventricular assist device in heart failure patients. Chin Med J. 2008;121(10):877–80.

    PubMed  Google Scholar 

  34. LE Samuels, Holmes EC, Thomas MP, Entwistle JC III, Morris RJ, Narula J, et al. Management of acute cardiac failure with mechanical assist: experience with the ABIOMED BVS 5000. Ann. Thorac. Surg. 2001;71(3 Suppl):S67–72. (discussion S82–5).

    Article  CAS  PubMed  Google Scholar 

  35. Samuels L, Entwistle J, Holmes E, Eaton D, Thomas MP, Menzano G, et al. Clinical use of the abiomed BVS 5000 as a pulsatile extracorporeal membrane oxygenation unit. ASAIO J. 2004;50(3):234–6.

    Article  PubMed  Google Scholar 

  36. Morgan JA, Stewart AS, Lee BJ, Oz MC, Naka Y. Role of the Abiomed BVS 5000 device for short-term support and bridge to transplantation. ASAIO J. 2004;50(4):360–3.

    PubMed  Google Scholar 

  37. Raess DH, Weber DM. Impella 2.5. J Cardiovasc Transl Res. 2009;2(2):168–72.

    Article  PubMed  Google Scholar 

  38. Thomopoulou S, Manginas A, Cokkinos DV. Initial experience with the Impella Recover LP 2.5 micro-axial pump in patients undergoing high-risk coronary angioplasty. Hellenic J Cardiol. 2008;49(6):382–7.

    PubMed  Google Scholar 

  39. Siegenthaler MP, Brehm K, Strecker T, Hanke T, Notzold A, Olschewski M, et al. The Impella recover microaxial left ventricular assist device reduces mortality for postcardiotomy failure: a three-center experience. J Thorac Cardiovasc Surg. 2004;127(3):812–22.

    Article  CAS  PubMed  Google Scholar 

  40. Desai NR, Bhatt DL. Evaluating percutaneous support for cardiogenic shock: data shock and sticker shock. Eur Heart J. 2009;30(17):2073–5.

    Article  PubMed  Google Scholar 

  41. Seyfarth M, Sibbing D, Bauer I, Frohlich G, Bott-Flugel L, Byrne R, et al. A randomized clinical trial to evaluate the safety and efficacy of a percutaneous left ventricular assist device versus intra-aortic balloon pumping for treatment of cardiogenic shock caused by myocardial infarction. J Am Coll Cardiol. 2008;52(19):1584–8.

    Article  PubMed  Google Scholar 

  42. Samoukovic G, Rosu C, Giannetti N, Cecere R. The Impella LP 5.0 as a bridge to long-term circulatory support. Interact Cardiovasc Thorac Surg. 2009;8(6):682–3.

    Article  PubMed  Google Scholar 

  43. Frazier OH, Myers TJ, Jarvik RK, Westaby S, Pigott DW, Gregoric ID, et al. Research and development of an implantable, axial-flow left ventricular assist device: the Jarvik 2000 Heart. Ann Thorac Surg. 2001;71(3 Suppl):S125–32. (discussion S44–6).

    Article  CAS  PubMed  Google Scholar 

  44. Siegenthaler MP, Frazier OH, Beyersdorf F, Martin J, Laks H, Elefteriades J, et al. Mechanical reliability of the Jarvik 2000 Heart. Ann Thorac Surg. 2006;81(5):1752–8. (discussion 8–9).

    Article  PubMed  Google Scholar 

  45. Frazier OH, Rose EA, Oz MC, Dembitsky W, McCarthy P, Radovancevic B, et al. Multicenter clinical evaluation of the HeartMate vented electric left ventricular assist system in patients awaiting heart transplantation. J Thorac Cardiovasc Surg. 2001;122(6):1186–95.

    Article  CAS  PubMed  Google Scholar 

  46. Slaughter MS, Sobieski MA II, Tamez D, Horrell T, Graham J, Pappas PS, et al. HeartWare miniature axial-flow ventricular assist device: design and initial feasibility test. Tex Heart Inst J Tex Heart Inst St. 2009;36(1):12–6.

    Google Scholar 

  47. Larose JA, Tamez D, Ashenuga M, Reyes C. Design concepts and principle of operation of the HeartWare ventricular assist system. ASAIO J. 2010;56(4):285–9.

    PubMed  Google Scholar 

  48. Tuzun E, Roberts K, Cohn WE, Sargin M, Gemmato CJ, Radovancevic B, et al. In vivo evaluation of the HeartWare centrifugal ventricular assist device. Tex Heart Inst J Tex Heart Inst St. 2007;34(4):406–11.

    Google Scholar 

  49. Wieselthaler GM, O’Driscoll G, Jansz P, Khaghani A, Strueber M. Initial clinical experience with a novel left ventricular assist device with a magnetically levitated rotor in a multi-institutional trial. J Heart Lung Transpl. 2010;29(11):1218–25.

    Article  Google Scholar 

  50. Strueber M, Meyer AL, Malehsa D, Haverich A. Successful use of the HeartWare HVAD rotary blood pump for biventricular support. J Thorac Cardiovasc Surg. 2010;140(4):936–7.

    Article  PubMed  Google Scholar 

  51. Miera O, Potapov EV, Redlin M, Stepanenko A, Berger F, Hetzer R, et al. First experiences with the HeartWare ventricular assist system in children. Ann Thorac Surg. 2011;91(4):1256–60.

    Article  PubMed  Google Scholar 

  52. Krabatsch T, Hennig E, Stepanenko A, Schweiger M, Kukucka M, Huebler M, et al. Evaluation of the HeartWare HVAD centrifugal pump for right ventricular assistance in an in vitro model. ASAIO J. 2011;57(3):183–7.

    Article  PubMed  Google Scholar 

  53. De Robertis F, Birks EJ, Rogers P, Dreyfus G, Pepper JR, Khaghani A. Clinical performance with the Levitronix Centrimag short-term ventricular assist device. J Heart Lung Transpl. 2006;25(2):181–6.

    Article  Google Scholar 

  54. Mueller JP, Kuenzli A, Reuthebuch O, Dasse K, Kent S, Zuend G, et al. The CentriMag: a new optimized centrifugal blood pump with levitating impeller. Heart Surg Forum. 2004;7(5):E477–80.

    Article  PubMed  Google Scholar 

  55. John R, Liao K, Lietz K, Kamdar F, Colvin-Adams M, Boyle A, et al. Experience with the Levitronix CentriMag circulatory support system as a bridge to decision in patients with refractory acute cardiogenic shock and multisystem organ failure. J Thorac Cardiovasc Surg. 2007;134(2):351–8.

    Article  PubMed  Google Scholar 

  56. Santise G, Petrou M, Pepper JR, Dreyfus G, Khaghani A, Birks EJ. Levitronix as a short-term salvage treatment for primary graft failure after heart transplantation. J Heart Lung Transpl. 2006;25(5):495–8.

    Article  Google Scholar 

  57. De Robertis F, Rogers P, Amrani M, Petrou M, Pepper JR, Bahrami T, et al. Bridge to decision using the Levitronix CentriMag short-term ventricular assist device. J Heart Lung Transpl. 2008;27(5):474–8.

    Article  Google Scholar 

  58. Hoefer D, Ruttmann E, Poelzl G, Kilo J, Hoermann C, Margreiter R, et al. Outcome evaluation of the bridge-to-bridge concept in patients with cardiogenic shock. Ann Thorac Surg. 2006;82(1):28–33.

    Article  PubMed  Google Scholar 

  59. Haj-Yahia S, Birks EJ, Amrani M, Petrou M, Bahrami T, Dreyfus G, et al. Bridging patients after salvage from bridge to decision directly to transplant by means of prolonged support with the CentriMag short-term centrifugal pump. J Thorac Cardiovasc Surg. 2009;138(1):227–30.

    Article  PubMed  Google Scholar 

  60. Meyer A, Slaughter M. The total artificial heart. Panminerva Medica. 2011;53(3):141–54.

    CAS  PubMed  Google Scholar 

  61. Arabia FA, Copeland JG, Smith RG, Sethi GK, Arzouman DA, Pavie A, et al. International experience with the CardioWest total artificial heart as a bridge to heart transplantation. Eur J Cardiothorac Surg. 1997;11(Suppl):S5–10.

    Article  PubMed  Google Scholar 

  62. El-Hamamsy I, Jacques F, Perrault LP, Bouchard D, Demers P, White M, et al. Results following implantation of mechanical circulatory support systems: the Montreal Heart Institute experience. Can J Cardiol. 2009;25(2):107–10.

    Article  PubMed  PubMed Central  Google Scholar 

  63. Nicholson C, Paz JC. Total artificial heart and physical therapy management. Cardiopulm Phys Therapy J. 2010;21(2):13–21.

    Google Scholar 

  64. Copeland JG, Smith RG, Arabia FA, Nolan PE, Sethi GK, Tsau PH, et al. Cardiac replacement with a total artificial heart as a bridge to transplantation. N Engl J Med. 2004;351(9):859–67.

    Article  CAS  PubMed  Google Scholar 

  65. Copeland JG III, Smith RG, Arabia FA, Nolan PE, Mehta VK, McCarthy, et al. Comparison of the CardioWest total artificial heart, the novacor left ventricular assist system and the thoratec ventricular assist system in bridge to transplantation. Ann Thorac Surg. 2001;71(3 Suppl):S92–7. (discussion S114–5).

    Article  PubMed  Google Scholar 

  66. Copeland JG, Smith RG, Bose RK, Tsau PH, Nolan PE, Slepian MJ. Risk factor analysis for bridge to transplantation with the CardioWest total artificial heart. Ann Thoracic Surg. 2008;85(5):1639–44.

    Article  Google Scholar 

  67. Taylor DO, Edwards LB, Aurora P, Christie JD, Dobbels F, Kirk R, et al. Registry of the International Society for Heart and Lung Transplantation: twenty-fifth official adult heart transplant report–2008. J Heart Lung Transpl. 2008;27(9):943–56.

    Article  Google Scholar 

  68. Pal JD, Piacentino V, Cuevas AD, Depp T, Daneshmand MA, Hernandez AF, et al. Impact of left ventricular assist device bridging on posttransplant outcomes. Ann Thoracic Surg. 2009;88(5):1457–61. (discussion 61).

    Article  Google Scholar 

  69. Drakos SG, Kfoury AG, Long JW, Stringham JC, Gilbert EM, Moore SA, et al. Effect of mechanical circulatory support on outcomes after heart transplantation. J Heart Lung Transpl. 2006;25(1):22–8.

    Article  Google Scholar 

  70. Cleveland JC Jr, Grover FL, Fullerton DA, Campbell DN, Mitchell MB, Lindenfeld J, et al. Left ventricular assist device as bridge to transplantation does not adversely affect one-year heart transplantation survival. J Thorac Cardiovasc Surg. 2008;136(3):774–7.

    Article  PubMed  Google Scholar 

  71. Patlolla V, Patten RD, Denofrio D, Konstam MA, Krishnamani R. The effect of ventricular assist devices on post-transplant mortality an analysis of the United network for organ sharing thoracic registry. J Am Coll Cardiol. 2009;53(3):264–71.

    Article  PubMed  Google Scholar 

  72. Gammie JS, Edwards LB, Griffith BP, Pierson RN III, Tsao L. Optimal timing of cardiac transplantation after ventricular assist device implantation. J Thorac Cardiovasc Surg. 2004;127(6):1789–99.

    Article  PubMed  Google Scholar 

  73. Taylor DO, Edwards LB, Boucek MM, Trulock EP, Waltz DA, Keck BM, et al. Registry of the International Society for Heart and Lung Transplantation: twenty-third official adult heart transplantation report—2006. J Heart Lung Transpl. 2006;25(8):869–79.

    Article  Google Scholar 

  74. Jaski BE, Kim JC, Naftel DC, Jarcho J, Costanzo MR, Eisen HJ, et al. Cardiac transplant outcome of patients supported on left ventricular assist device vs. intravenous inotropic therapy. J Heart Lung Transpl. 2001;20(4):449–56.

    Article  CAS  Google Scholar 

  75. Frazier OH, Rose EA, McCarthy P, Burton NA, Tector A, Levin H, et al. Improved mortality and rehabilitation of transplant candidates treated with a long-term implantable left ventricular assist system. Ann Surg. 1995;222(3):327–36. (discussion 36–8).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  76. Lietz K. Destination therapy: patient selection and current outcomes. J Cardiac Surg. 2010;25(4):462–71.

    Article  Google Scholar 

  77. Lund LH, Matthews J, Aaronson K. Patient selection for left ventricular assist devices. Eur J Heart Fail. 2010;12(5):434–43.

    Article  PubMed  Google Scholar 

  78. Lietz K, Miller LW. Patient selection for left-ventricular assist devices. Curr Opin Cardiol. 2009;24(3):246–51.

    Article  PubMed  Google Scholar 

  79. Chinn R, Dembitsky W, Eaton L, Chillcott S, Stahovich M, Rasmusson B, et al. Multicenter experience: prevention and management of left ventricular assist device infections. ASAIO J. 2005;51(4):461–70.

    Article  PubMed  Google Scholar 

  80. Weitkemper HH, El-Banayosy A, Arusoglu L, Sarnowski P, Korfer R. Mechanical circulatory support: reality and dreams experience of a single center. J Extracorporeal Technol. 2004;36(2):169–73.

    CAS  Google Scholar 

  81. Holman WL, Kormos RL, Naftel DC, Miller MA, Pagani FD, Blume E, et al. Predictors of death and transplant in patients with a mechanical circulatory support device: a multi-institutional study. J Heart Lung Transpl. 2009;28(1):44–50.

    Article  Google Scholar 

  82. Slaughter MS, Tsui SS, El-Banayosy A, Sun BC, Kormos RL, Mueller DK, et al. Results of a multicenter clinical trial with the Thoratec implantable ventricular assist device. J Thorac Cardiovasc Surg. 2007;133(6):1573–80.

    Article  PubMed  Google Scholar 

  83. Frazier OH, Rose EA, Macmanus Q, Burton NA, Lefrak EA, Poirier VL, et al. Multicenter clinical evaluation of the HeartMate 1000 IP left ventricular assist device. Ann Thorac Surg. 1992;53(6):1080–90.

    Article  CAS  PubMed  Google Scholar 

  84. Gheorghiade M, Abraham WT, Albert NM, Greenberg BH, O’Connor CM, She L, et al. Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure. JAMA. 2006;296(18):2217–26.

    Article  CAS  PubMed  Google Scholar 

  85. Zannad F, Mebazaa A, Juilliere Y, Cohen-Solal A, Guize L, Alla F, et al. Clinical profile, contemporary management and one-year mortality in patients with severe acute heart failure syndromes: the EFICA study. Eur J Heart Fail. 2006;8(7):697–705.

    Article  PubMed  Google Scholar 

  86. Shiga T, Kinugawa K, Hatano M, Yao A, Nishimura T, Endo M, et al. Age and preoperative total bilirubin level can stratify prognosis after extracorporeal pulsatile left ventricular assist device implantation. Circ J. 2010;75(1):121–8.

    Article  PubMed  Google Scholar 

  87. Fonarow GC, Adams KF Jr, Abraham WT, Yancy CW, Boscardin WJ. Risk stratification for in-hospital mortality in acutely decompensated heart failure: classification and regression tree analysis. JAMA. 2005;293(5):572–80.

    Article  CAS  PubMed  Google Scholar 

  88. Kirklin JK, Naftel DC, Stevenson LW, Kormos RL, Pagani FD, Miller MA, et al. INTERMACS database for durable devices for circulatory support: first annual report. J Heart Lung Transpl. 2008;27(10):1065–72.

    Article  Google Scholar 

  89. Goldstein DJ, Oz MC, Rose EA. Implantable left ventricular assist devices. N Engl J Med. 1998;339(21):1522–33.

    Article  CAS  PubMed  Google Scholar 

  90. Arai H, Swartz MT, Pennington DG, Moriyama Y, Miller L, Peigh P, et al. Importance of ventricular arrhythmias in bridge patients with ventricular assist devices. ASAIO Trans Am Soc Artif Intern Organs. 1991;37(3):M427–8.

    CAS  Google Scholar 

  91. Zipes DP, Camm AJ, Borggrefe M, Buxton AE, Chaitman B, Fromer M, et al. ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (writing committee to develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death): developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society. Circulation. 2006;114(10):e385–484.

    Article  PubMed  Google Scholar 

  92. Bogale N, Priori S, Cleland JG, Brugada J, Linde C, Auricchio A, et al. The European CRT Survey: 1 year (9–15 months) follow-up results. Eur J Heart Failure. 2012;14(1):61–73.

    Article  Google Scholar 

  93. Lau CP, Barold S, Tse HF, Lee KL, Chan HW, Fan K, et al. Advances in devices for cardiac resynchronization in heart failure. J Interv Card Electrophysiol. 2003;9(2):167–81.

    Article  PubMed  Google Scholar 

  94. Cleland JG, Daubert JC, Erdmann E, Freemantle N, Gras D, Kappenberger L, et al. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med. 2005;352(15):1539–49.

    Article  CAS  PubMed  Google Scholar 

  95. Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T, et al. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med. 2004;350(21):2140–50.

    Article  CAS  PubMed  Google Scholar 

  96. Cannom DS, Prystowsky EN. Evolution of the implantable cardioverter defibrillator. J Cardiovasc Electrophysiol. 2004;15(3):375–85.

    Article  PubMed  Google Scholar 

  97. Bai R, Di Biase L, Elayi C, Ching CK, Barrett C, Philipps K, et al. Mortality of heart failure patients after cardiac resynchronization therapy: identification of predictors. J Cardiovasc Electrophysiol. 2008;19(12):1259–65.

    Article  PubMed  Google Scholar 

  98. Lam SK, Owen A. Combined resynchronisation and implantable defibrillator therapy in left ventricular dysfunction: Bayesian network meta-analysis of randomised controlled trials. BMJ (Clin Res Ed). 2007;335(7626):925.

    Article  Google Scholar 

  99. Vardas PE, Auricchio A, Blanc JJ, Daubert JC, Drexler H, Ector H, et al. Guidelines for cardiac pacing and cardiac resynchronization therapy: the Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in collaboration with the European Heart Rhythm Association. Eur Heart J. 2007;28(18):2256–95.

    Article  PubMed  Google Scholar 

  100. Epstein AE, DiMarco JP, Ellenbogen KA, Estes NA 3rd, Freedman RA, Gettes LS, et al. ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices): developed in collaboration with the American Association for Thoracic Surgery and Society of Thoracic Surgeons. Circulation. 2008;117(21):e350–408.

    Article  PubMed  Google Scholar 

  101. Boriani G, Gasparini M, Landolina M, Lunati M, Biffi M, Santini M, et al. Impact of mitral regurgitation on the outcome of patients treated with cRT-D: data from the InSync ICD Italian Registry. Pacing Clin Electrophysiol 2012;35(2):146–54

    Google Scholar 

  102. Mancini D, Burkhoff D. Mechanical device-based methods of managing and treating heart failure. Circulation. 2005;112(3):438–48.

    Article  PubMed  Google Scholar 

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Dr. Siyamek Neragi-Miandoab has no conflict of interest.

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  1. Department of Cardiovascular and Thoracic Surgery, Albert Einstein College of Medicine, Montefiore Medical Center, 3400 Bainbridge Ave, MAP 5 Building, Bronx, NY, 10467, USA

    Siyamek Neragi-Miandoab

  2. 3450 Wayne Ave, Apt 24 J, Bronx, NY, 10467, USA

    Siyamek Neragi-Miandoab

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Correspondence to Siyamek Neragi-Miandoab.

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Neragi-Miandoab, S. A ventricular assist device as a bridge to recovery, decision making, or transplantation in patients with advanced cardiac failure. Surg Today 42, 917–926 (2012). https://doi.org/10.1007/s00595-012-0256-z

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  • DOI: https://doi.org/10.1007/s00595-012-0256-z

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