Lumbar spine fusion surgery and stroke: a national cohort study
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
To investigate the incidence and risk of stroke after lumbar spinal fusion surgery.
Study subjects were identified from a nationwide cohort of 1 million people from 2000 to 2005 and were divided into the lumbar spinal fusion group (n = 2,015), who received posterior lumbar spinal fusion surgery, and the comparison group (n = 16,120) composed of age-, sex-, and propensity score-matched control subjects. The matching process was intended to adjust for demographics, comorbidities, and other immeasurable covariates to minimize selection bias. All subjects were followed up for 3 years for stroke, including hemorrhagic and ischemic strokes. Kaplan–Meier and Cox regression analyses were performed.
The overall incidence rate of stroke in the cohort was 9.99 per 1,000 person-year. The lumbar spinal fusion group was less likely to have any stroke (adjusted hazard ratio (HR) = 0.83, p = 0.293), hemorrhagic stroke (adjusted HR = 0.74, p = 0.739) and ischemic stroke (adjusted HR = 0.81, p = 0.250) than the comparison group, but without significance.
Three years post-operatively, patients who received lumbar spinal fusion had stroke incidence rates similar to those without surgery. Posterior lumbar spinal fusion surgery is not associated with increased risks for any kind of stroke.
- Lumbar spine fusion surgery and stroke: a national cohort study
European Spine Journal
Volume 21, Issue 12 , pp 2680-2687
- Cover Date
- Print ISSN
- Online ISSN
- Additional Links
- Cerebrovascular accident
- Hemorrhagic stroke
- Ischemic stroke
- Lumbar fusion
- Industry Sectors
- Author Affiliations
- 2. Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
- 3. School of Medicine, National Yang-Ming University, Taipei, Taiwan
- 4. Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan
- 1. Department of Medical Research and Education, National Yang-Ming University Hospital, No. 152, Xin Min Rd, 26042, I-Lan, Taiwan
- 8. Institute of Hospital and Health Care Administration, School of Medicine, National Yang-Ming University, Taipei, Taiwan
- 5. Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
- 6. College of Medicine, Chang Gung University, Taoyuan, Taiwan
- 7. Department of Pediatrics, National Yang-Ming University Hospital, I-Lan, Taiwan
- 9. Department of Surgery, School of Medicine, National Yang-Ming University, Taipei, Taiwan