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Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial)

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Abstract

Purpose

The aim of this study was to evaluate the effects of a preoperative popliteal block on sevoflurane consumption, postoperative pain, and analgesic consumption in children with cerebral palsy (CP) following lower limb surgery.

Methods

Fifty-four patients undergoing lower limb surgery were randomized to receive either a popliteal block + general anaesthesia (group P, n = 27) or general anaesthesia without a popliteal block (group C, n = 27). After anesthesia induction with 50% N2O, O2, and 8% sevoflurane, a popliteal block was given to group P patients with ultrasound guidance as a single dose of 0.3 ml/kg body weight of 0.25% bupivacaine. Group C patients received the same regimen of anesthesia induction but no preoperative popliteal block. Both the conductance fluctuation (SCF) peak numbers per second and the Wong–Baker FACES® Pain Rating Scale (WBFS) values of the patients were recorded upon arrival at the PACU, at 10 and 20 min after arrival at the PACU, and at postoperative hours 1, 4, 8, 12, and 24 when they were in the ward. The total paracetamol consumption of the patients was also recorded.

Results

The end-tidal sevoflurane concentration values were significantly higher in group C patients than in group P patients, except for at 5 min after induction of anaesthesia (p < 0.001). The SCF peak numbers per second and WBFS scores were significantly higher in group C patients than in group P patients, except at Tp24h (p < 0.001). The total paracetamol consumption was 489.7 ± 122.7 mg in group P patients and 816.6 ± 166.5 in group C patients (p < 0.001).

Conclusion

Popliteal block is effective for postoperative analgesia, decreasing the paracetamol consumption and sevoflurane requirement in children with CP undergoing lower limb surgery.

Trial registration ClinicalTrial.gov identifier: NCT02507700.

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References

  1. Nolan J, Chalkiadis GA, Low J, Olesch CA, Brown TC. Anaesthesia and pain management in cerebral palsy. Anaesthesia. 2000;55:32–41.

    Article  CAS  PubMed  Google Scholar 

  2. Nemeth BA, Montero RJ, Halanski MA, Noonan KJ. Epidural Baclofen for the management of postoperative pain in children with cerebral palsy. J Pediatr Orthop. 2015;35(6):571–5.

    Article  PubMed  Google Scholar 

  3. Shrader MW, Jones J, Falk MN, White GR, Burk DR, Segal LS. Hip reconstruction is more painful than spine fusion in children with cerebral palsy. J Child Orthop. 2015;9(3):221–5.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Petroheilou K, Livanios S, Zavras N, Hager J, Fassoulaki A. Sciatic lateral popliteal block with clonidine alone or clonidine plus 0.2% ropivacaine: effect on the intra-and postoperative analgesia for lower extremity surgery in children: a randomized prospective controlled study. BMC Anesthesiol. 2012;12:2.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Drendel AL, Kelly BT, Ali S. Pain assessment for children: overcoming challenges and optimizing care. Pediatr Emerg Care. 2011;27:773–81.

    Article  PubMed  Google Scholar 

  6. Storm H. Changes in skin conductance as a tool to monitor nociceptive stimulation and pain. Curr Opin Anaesthesiol. 2008;21:796–804.

    Article  PubMed  Google Scholar 

  7. Ledowski T, Bromilow J, Wu J, Paech MJ, Storm H, Schug SA. The assessment of postoperative pain by monitoring skin conductance: results of a prospective study. Anaesthesia. 2007;62:989–93.

    Article  CAS  PubMed  Google Scholar 

  8. Hagbarth KE, Hallin RG, Hongell A, Torebjörk HE, Wallin BG. General characteristics of sympathetic activity in human skin nerves. Acta Physiol Scand. 1972;84:164–76.

    Article  CAS  PubMed  Google Scholar 

  9. Wong DL, Baker CM. Pain in children: comparison of assessment scales. Okla Nurse. 1988;33:8.

    CAS  PubMed  Google Scholar 

  10. Buys MJ, Arndt CD, Vagh F, Hoard A, Gerstein N. Ultrasound-guided sciatic nerve block in the popliteal fossa using a lateral approach: onset time comparing separate tibial and common peroneal nerve injections versus injecting proximal to the bifurcation. Anesth Analg. 2010;110:635–7.

    Article  PubMed  Google Scholar 

  11. Aldrete JA. The post-anesthesia recovery score revisited. J Clin Anesth. 1995;7:89–91.

    Article  CAS  PubMed  Google Scholar 

  12. Maranhao MVM. Anesthesia and cerebral palsy. Rev Bras Anestesiol. 2005;55(6):680–702.

    Article  PubMed  Google Scholar 

  13. Capjon H, Bjørk IT. Ambulant children with spastic cerebral palsy and their parents’ perceptions and expectations prior to multilevel surgery. Dev Neurorehabil. 2010;13(2):80–7.

    Article  PubMed  Google Scholar 

  14. Nielsen DM, Gill K, Ricketts DM. Satisfaction levels in orthopaedic out-patients. Ann R Coll Surg Engl. 2005;87(2):106–8.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Collignon P, Giusiano B. Validation of a pain evaluation scale for patients with severe cerebral palsy. Eur J Pain. 2001;5:433–42.

    Article  CAS  PubMed  Google Scholar 

  16. Breau LM, Camfield CS, McGrath PJ, Finley GA. The incidence of pain in children with severe cognitive impairments. Arch Pediatr Adolesc Med. 2003;157:1219–26.

    Article  PubMed  Google Scholar 

  17. Russo RN, Miller MD, Haan E, Cameron ID, Crotty M. Pain characteristics and their association with quality of life and self-concept in children with hemiplegic cerebral palsy identified from a population register. Clin J Pain. 2008;24(4):335–42.

    Article  PubMed  Google Scholar 

  18. Oberlander TF, O’Donnell ME, Montgomery CJ. Pain in children with significant neurological impairment. J Dev Behav Pediatr. 1999;20:235–43.

    Article  CAS  PubMed  Google Scholar 

  19. Chou R, Gordon DB, de Leon-Casasola OA, Rosenberg JM, Bickler S, Brennan T, Carter T, Cassidy CL, Chittenden EH, Degenhardt E, Griffith S, Manworren R, McCarberg B, Montgomery R, Murphy J, Perkal MF, Suresh S, Sluka K, Strassels S, Thirlby R, Viscusi E, Walco GA, Warner L, Weisman SJ, Wu CL. Management of postoperative pain: a Clinical Practice Guideline from the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists’ Committee on Regional Anesthesia, Executive Committee, and Administrative Council. J Pain. 2016;17(2):131–57.

    Article  PubMed  Google Scholar 

  20. Jabbari B. Botilinum toxins for treatment of pain in orthopedic disorders. In: Jabbary B, editor. Botilinum toxin treatment of pain disorders. New York: Springer Science+Business Media; 2015. p. 193–204.

  21. Barwood S, Baillieu C, Boyd R, Brereton K, Low J, Nattrass G, Graham HK. Analgesic effects of botulinum toxin A: a randomized, placebo-controlled clinical trial. Dev Med Child Neurol. 2000;42:116–21.

    Article  CAS  PubMed  Google Scholar 

  22. Oberndorfer U, Marhofer P, Bösenberg A, Willschke H, Felfernig M, Weintraud M, Kapral S, Kettner SC. Ultrasonographic guidance for sciatic and femoral nevre blocks in children. Br J Anaesth. 2007;98:797–801.

    Article  CAS  PubMed  Google Scholar 

  23. Lewis SR, Price A, Walker KJ, McGrattan K, Smith AF. Ultrasound guidance for upper and lower limb blocks. Cochrane Database Syst Rev. 2015;11:CD006459.

    Google Scholar 

  24. Bosenberg A, Thomas J, Lopez T, Kokinsky E, Larsson LE. Validation of a six-graded faces scale for evaluation of postoperative pain in children. Paediatr Anaesth. 2003;13:708–13.

    Article  CAS  PubMed  Google Scholar 

  25. Guignard B. Monitoring analgesia. Best Pract Res Clin Anaesthesiol. 2006;20:161–80.

    Article  PubMed  Google Scholar 

  26. Storm H, Shafiei M, Myre K, Raeder J. Palmar skin conductance compared to a developed stress score and to noxious and awakening stimuli on patients in anaesthesia. Acta Anaesthesiol Scand. 2005;49:798–803.

    Article  CAS  PubMed  Google Scholar 

  27. Choo EK, Magruder W, Montgomery CJ, Lim J, Brant R, Ansermino JM. Skin conductance fluctuations correlate poorly with postoperative self-report pain measures in school-aged children. Anesthesiology. 2010;113:175–82.

    Article  PubMed  Google Scholar 

  28. Hullett B, Chambers N, Preuss J, Zamudio I, Lange J, Pascoe E, Ledowski T. Monitoring electrical skin conductance: a tool for the assessment of postoperative pain in children? Anesthesiology. 2009;111:513–7.

    Article  PubMed  Google Scholar 

  29. Kim SH, Chun DH, Chang CH, Kim TW, Kim YM, Shin YS. Effect of caudal block on sevoflurane requirement for lower limb surgery in children with cerebral palsy. Paediatr Anaesth. 2011;21:394–8.

    Article  PubMed  Google Scholar 

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Correspondence to Derya Ozkan.

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Ozkan, D., Gonen, E., Akkaya, T. et al. Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial). J Anesth 31, 358–364 (2017). https://doi.org/10.1007/s00540-017-2318-2

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  • DOI: https://doi.org/10.1007/s00540-017-2318-2

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