Skip to main content
Log in

Low-dose spinal–epidural anesthesia for Cesarean section in a parturient with uncontrolled hyperthyroidism and thyrotoxic heart disease

  • Clinical Report
  • Published:
Journal of Anesthesia Aims and scope Submit manuscript

Abstract

A 29-year-old woman at 34 weeks’ gestation with uncontrolled hyperthyroidism and thyrotoxic heart disease was admitted to urgency Cesarean section. After preoperative sedation and good communication, low-dose spinal anesthesia (7.5 mg 0.5 % bupivacaine) combined with epidural anesthesia (6 ml 2 % lidocaine) was performed through L3–4 inter-vertebral. Opioids were given intravenously to the mother for sedation after delivery of the baby. Satisfactory anesthesia and sedation was provided during surgery. The mother and the neonate were safe and no special complication was found after surgery. Our case demonstrated that low-dose spinal anesthesia combined with epidural anesthesia with intravenous opioids can provide satisfactory anesthesia and sedation, and reduce the risk of heart failure and thyroid storm.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Carney LA, Quinlan JD, West JM. Thyroid disease in pregnancy. Am Fam Physician. 2014;89(4):273–8.

    PubMed  Google Scholar 

  2. Stagnaro-Green A, Pearce E. Thyroid disorders in pregnancy. Nat Rev Endocrinol. 2012;8(11):650–8.

    Article  CAS  PubMed  Google Scholar 

  3. Krassas G, Karras SN, Pontikides N. Thyroid diseases during pregnancy: a number of important issues. Hormones (Athens). 2015;14(1):59–69.

    Google Scholar 

  4. Kalelioqlu IH, Has R, Ciqerli E, Ermis BH, Ibrahimoqlu EL, Yildirim A, Kubat A, Yuksel A. Heart failure caused by thyrotoxicosis in pregnancy—case report. Clin Exp Obstet Gynecol. 2007;34(2):117–9.

    Google Scholar 

  5. Sheffield JS, Cunningham FG. Thyrotoxicosis and heart failure that complicate pregnancy. Am J Obstet Gynecol. 2004;190(1):211–7.

    Article  PubMed  Google Scholar 

  6. Reschke K, Lehnert H. Thyroid crisis. Internist (Berl). 2003;44(10):1221–30.

    Article  CAS  Google Scholar 

  7. Erturk E, Bostan H, Geze S, Saracoglu S, Erciyes N, Eroglu A. Total intravenous anesthesia for evacuation of a hydatidiform mole and termination of pregnancy in a patient with thyrotoxicosis. Int J Obstet Anesth. 2007;16(4):363–6.

    Article  CAS  PubMed  Google Scholar 

  8. Matsumoto S, Shingu C, Hidaka S, Goto K, Hagiwara S, Iwasaka H, Noguchi T. Anesthetic management of a patient with hyperthyroidism due to hydatidiform mole. J Anesth. 2009;23(4):594–6.

    Article  PubMed  Google Scholar 

  9. Hirvo EA, Nisk LK, Nisk MM. Thyroid storm prior to induction of anaesthesia. Anaesthesia. 2004;59:1020–2.

    Article  Google Scholar 

  10. Pugh S, Lalwani K, Awal A. Thyroid storm as a cause of loss of consciousness following anaesthesia for emergency Caesarean section. Anaesthesia. 1994;49:35–7.

    Article  CAS  PubMed  Google Scholar 

  11. Varela A, Yuste A, Villazala R, Garrido J, Lorenzo A, Lopez E. Spinal anesthesia for emergency abdominal surgery in uncontrolled hyperthyroidism. Acta Anaesthesiol Scand. 2005;49(1):100–3.

    Article  CAS  PubMed  Google Scholar 

  12. Stuijver DJ, van Zaane B, Romualdi E, Brandjes DP, Gerdes VE, Squizzato A. The effect of hyperthyroidism on procoagulant, anticoagulant and fibrinolytic factors: a systematic review and meta-analysis. Thromb Haemost. 2012;108(6):1077–88.

    Article  PubMed  Google Scholar 

  13. Debeij J, van Zaane B, Dekkers OM, Doggen CJ, Smit JW, van Zanten AP, Brandjes DP, Büller HR, Gerdes VE, Rosendaal FR, Cannegieter SC. High levels of procoagulant factors mediate the association between free thyroxine and the risk of venous thrombosis: the MEGA study. J Thromb Haemost. 2014;12(6):839–46.

    Article  CAS  PubMed  Google Scholar 

  14. Yamazaki Y, Saito A, Hasegawa K, Takahashi H. Aggravation of congestive heart failure after cesarean section in a patient with undiscovered hyperthyroidism (in Japanese with English abstract). Masui. 2006;55(11):1404–8.

    PubMed  Google Scholar 

  15. Farling PA. Thyroid disease. Br J Anaesth. 2000;85:15–28.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Linli Luo.

Ethics declarations

Conflict of interest

The authors have no conflicts of interest.

Additional information

Z. Liao and Y. Xiong contributed equally to this work and should be considered co-first authors.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Liao, Z., Xiong, Y. & Luo, L. Low-dose spinal–epidural anesthesia for Cesarean section in a parturient with uncontrolled hyperthyroidism and thyrotoxic heart disease. J Anesth 30, 731–734 (2016). https://doi.org/10.1007/s00540-016-2186-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00540-016-2186-1

Keywords

Navigation