Journal of Gastroenterology

, Volume 49, Issue 1, pp 73–80

The ability of a novel blue laser imaging system for the diagnosis of invasion depth of colorectal neoplasms

  • Naohisa Yoshida
  • Takashi Hisabe
  • Yutaka Inada
  • Munehiro Kugai
  • Nobuaki Yagi
  • Fumihito Hirai
  • Kenshi Yao
  • Toshiyuki Matsui
  • Akinori Iwashita
  • Mototsugu Kato
  • Akio Yanagisawa
  • Yuji Naito
Original Article—Alimentary Tract

DOI: 10.1007/s00535-013-0772-7

Cite this article as:
Yoshida, N., Hisabe, T., Inada, Y. et al. J Gastroenterol (2014) 49: 73. doi:10.1007/s00535-013-0772-7

Abstract

Background

Fujifilm has developed a novel endoscope system with two kinds of lasers that enables us to allow narrow-band light observation with blue laser imaging (BLI). The aim of this study was to evaluate BLI magnification in comparison with narrow-band imaging (NBI) magnification for the diagnosis of colorectal neoplasms.

Methods

This was a multicenter open study. A total of 104 colorectal neoplasms were examined with BLI and NBI magnifications in Kyoto Prefectural University of Medicine and Fukuoka University Chikushi Hospital. Vascular and surface patterns of tumors under BLI magnification were compared with those under NBI magnification, using a published NBI classification. The main outcome was the correlation between the NBI classification diagnosed by BLI or NBI magnification and the histopathological analyses.

Results

Sixty-two cases of adenoma, 34 cases of intramucosal cancer and shallowly invaded submucosal cancer, and eight cases of deeply invaded submucosal cancer were diagnosed. The diagnostic accuracy of BLI magnification in the NBI classification was 74.0 % (77/104), similar to that of NBI magnification (77.8 %). The consistency rate between BLI and NBI magnification in the NBI classification was 74.0 %. Concerning image evaluation, the interobserver variability of two expert endoscopists (N.Y. and T.H.) in BLI magnification was κ = 0.863. On the other hand, the intraobserver variability of the two endoscopists was κ = 0.893 (N.Y.) and 0.851 (T.H.).

Conclusions

BLI magnification by laser source could predict histopathological diagnosis and invasion depth of colorectal neoplasms. The diagnostic effectiveness of this method was similar to that of NBI magnification.

Keywords

BLILaserNBIColorectal polypsImage-enhanced endoscopy

Copyright information

© Springer Japan 2013

Authors and Affiliations

  • Naohisa Yoshida
    • 1
  • Takashi Hisabe
    • 2
  • Yutaka Inada
    • 1
  • Munehiro Kugai
    • 1
  • Nobuaki Yagi
    • 1
  • Fumihito Hirai
    • 2
  • Kenshi Yao
    • 2
  • Toshiyuki Matsui
    • 2
  • Akinori Iwashita
    • 3
  • Mototsugu Kato
    • 4
  • Akio Yanagisawa
    • 5
  • Yuji Naito
    • 1
  1. 1.Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical ScienceKyoto Prefectural University of MedicineKyotoJapan
  2. 2.Department of GastroenterologyFukuoka University Chikushi HospitalFukuokaJapan
  3. 3.Department of PathologyFukuoka University Chikushi HospitalFukuokaJapan
  4. 4.Department of EndoscopyHokkaido University HospitalHokkaidoJapan
  5. 5.Department of Surgical Pathology, Graduate School of Medical ScienceKyoto Prefectural University of MedicineKyotoJapan