Skip to main content
Log in

Post streptococcal acute glomerulonephritis secondary to sporadic Streptococcus equi infection

  • Brief Report
  • Published:
Pediatric Nephrology Aims and scope Submit manuscript

Abstract

Streptococcus equi subspecies zooepidemicus infection is rare in humans, but a well-known cause of pyogenic disease in cows and horses. S. zooepidemicus uncommonly causes post-strep glomerulonephritis (PSGN) in humans via epidemic outbreaks. We present a sporadic case of post S. zooepidemicus glomerulonephritis in a child most probably contracted from a horse. The 14-year-old girl presented with the typical signs of PSGN, with S. equi zooepidemicus isolated from a blood culture, together with a low C3 and raised anti-DNAse B. This is the first known report of a sporadic case of PSGN in a child caused by this organism.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Sweeney CR, Timoney JF, Newton JR, Hines MT (2005) Streptococcus equi infections in horses: guidelines for treatment, control and prevention of strangles. J Vet Intern Med 19:123–134

    Article  Google Scholar 

  2. Divers TJ, Timoney JF, Lewis RM, Smith CA (1992) Equine glomerulonephritis and renal failure associated with complexes of group C streptococcal antigen and IgG antibody. Vet Immunol Immunopathol 32:93–102

    Article  CAS  Google Scholar 

  3. Latorre M, Alvarez J, Fernandez M, Berdonces P, Llanos P, Cisterna R (1993) A case of meningitis due to Streptococcus zooepidemicus. Clin Infect Dis 17:932–933

    Article  CAS  Google Scholar 

  4. Rose HD, Allen JR, Witte G (1980) Streptococcus zooepidemicus (group C) pneumonia in a human. J Clin Microbiol 11:76–78

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Collazos J, Echevarria MJ, Ayarza R, Miguel J (1992) Streptococcus zooepidemicus septic arthritis: case report and review of group C streptococcal arthritis. Clin Infect Dis 15:744–746

    Article  CAS  Google Scholar 

  6. Martinez-Luengas F, Inclan GM, Pastor A, Montejo M, Barron J, Baroja A, Aguirre C (1982) Endocarditis due to Streptococcus zooepidemicus. Can Med Assoc J 127:13

    CAS  PubMed  PubMed Central  Google Scholar 

  7. Balter S, Benin A, Pinto SWL, Teixeira LM, Alvim GG, Luna E, Jackson D, LaClaire L, Elliott J, Facklam R, Schuchat A (2000) Epidemic nephritis in Nova Serrana, Brazil. Lancet 355:1776–1780

    Article  CAS  Google Scholar 

  8. Barnham M, Thorton TJ, Lange K (1983) Nephritis caused by strep zooepidemicus (Lancefield Group C). Lancet 1:945–948

    Article  CAS  Google Scholar 

  9. Barnham M, Ljunggen A, McIntyre M (1987) Human infection with streptococcus zooepidemicus (Lancefield group C): three case reports. Epidemiol Infect 98:183–190

    Article  CAS  Google Scholar 

  10. Low DE, Young MR, Harding GKM (1980) Group C streptococcal meningitis in an adult: probably acquisition from a horse. Arch Intern Med 140:977–978

    Article  CAS  Google Scholar 

  11. Dodge WF, Spargo BH, Travis LB, Srivastava RN, Carvajal HF, DeBeukelaer MM, Longley MP, Menchaca JA (1972) Poststreptococcal glomerulonephritis. A prospective study in children. N Engl J Med 286:273–278, Feb 10

    Article  CAS  Google Scholar 

  12. Francis AJ, Nimmo GR, Efstratiou A, Galanis V, Nuttall N (1993) Investigation of milk-borne Streptococcus zooepidemicus infection associated with glomerulonephritis in Australia. J Infect 27:317–323

    Article  CAS  Google Scholar 

  13. Edwards AT, Roulson M, Ironside MJ (1988) A milk-borne outbreak of serious infection due to Streptococcus zooepidemicus (Lancefield group C). Epidemiol Infect 101:43–51

    Article  CAS  Google Scholar 

  14. Lange K, Ahmed U, Kleinberger H, Treser G (1976) A hitherto unknown streptococcal antigen and its probable relation to acute poststreptococcal glomerulonephritis. Clin Nephrol 5:207–215

    CAS  PubMed  Google Scholar 

  15. Yoshizawa N, Yamazaki K, Fujino M, Oda T, Tamura K, Matsumoto K, Sugisaki T, Boyle MDP (2004) Nephritis-associated plasmin receptor and acute poststreptococcal glomerulonephritis: characterization of the antigen and associated immune response. J Am Soc Nephrol 15:1785–1793

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Anna M. Thorley.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Thorley, A.M., Campbell, D., Moghal, N.E. et al. Post streptococcal acute glomerulonephritis secondary to sporadic Streptococcus equi infection. Pediatr Nephrol 22, 597–599 (2007). https://doi.org/10.1007/s00467-006-0364-3

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00467-006-0364-3

Keywords

Navigation