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Acute acalculous cholecystitis in a child with systemic lupus erythematosus

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Abstract

A 10-year-old boy with systemic lupus erythematosus (SLE) developed abrupt right upper quadrant pain and vomiting during the course of his active disease. Antiphospholipid antibody was negative and the C3 level was low. Abdominal sonography showed cholecystitis with sludge balls in the gallbladder. He was treated by high-dose prednisolone with ceftriaxone and metronidazole IV for 3 days but due to poor response, cholecystectomy was performed and no stone was identified. Histopathologic examination showed vasculitis in the medium-sized arteries of the gallbladder wall. He was doing well at the 9-month follow-up after the operation. This report describes the first pediatric case of SLE with acalculous cholecystitis caused by vasculitis of the gallbladder.

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Acknowledgement

We would like to thank Dr. Sirus Arshadi for interpretation of the sonography in this case.

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Authors and Affiliations

  1. Department of Pediatric Nephrology, Nemazee Hospital, Shiraz Medical School, Shiraz, Iran

    Mitra Basiratnia & Ali Derakhshan

  2. Department of Pathology and Institute of Cancer Research, Shiraz Medical School, Shiraz, Iran, 71344

    Mohammad Vasei & Esmaeel Ebrahimi

  3. Department of Pediatric surgery, Nemazee hospital, Shiraz Medical School, Shiraz, Iran

    Ali Bahador

Authors
  1. Mitra Basiratnia
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  2. Mohammad Vasei
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  3. Ali Bahador
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  4. Esmaeel Ebrahimi
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  5. Ali Derakhshan
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Corresponding author

Correspondence to Mohammad Vasei.

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Basiratnia, M., Vasei, M., Bahador, A. et al. Acute acalculous cholecystitis in a child with systemic lupus erythematosus. Pediatr Nephrol 21, 873–876 (2006). https://doi.org/10.1007/s00467-006-0021-x

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  • DOI: https://doi.org/10.1007/s00467-006-0021-x

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