Skip to main content
SpringerLink
Log in

The high mobility group I-C gene (HMGI-C): polymorphism and genetic localization

  • Original investigation
  • Published:
Human Genetics Aims and scope Submit manuscript

Abstract

We have identified a highly informative dinucleotide repeat in the 5′-flanking region of the human high mobility group I-C (HMGI-C) gene. This polymorphism consists of 18–37 copies of a (CT) repeat with an observed heterozygosity of 82–83% in African Americans and Caucasians. Linkage analysis in CEPH pedigrees localized the HMGI-C gene to chromosome region 12q13–15 with no recombination observed between HMCI-C and markers D12S102 and D12S8.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Department of Human Genetics, Graduate School of Public Health, 130 De Soto Street, University of Pittsburgh, PA 15261, USA Tel.: + 1-412-624-3018; Fax: +1-412-624-3020, , , , , , US

    C. S. Ishwad, M. D. Shriver, D. M. Lassige & R. E. Ferrell

Authors
  1. C. S. Ishwad
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. D. Shriver
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. D. M. Lassige
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. E. Ferrell
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Received: 16 February 1996 / Revised: 30 April 1996, 29 July 1996

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ishwad, C., Shriver, M., Lassige, D. et al. The high mobility group I-C gene (HMGI-C): polymorphism and genetic localization. Hum Genet 99, 103–105 (1996). https://doi.org/10.1007/s004390050320

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s004390050320

Keywords

Search

Navigation