Human Genetics

, Volume 121, Issue 5, pp 631–633

A strong association between human earwax-type and apocrine colostrum secretion from the mammary gland

Authors

    • Department of Obstetrics and Gynaecology Nagasaki University Graduate School of Biomedical Sciences
  • Koh-ichiro Yoshiura
    • Department of Human Genetics Nagasaki University Graduate School of Biomedical Sciences
    • SORSTJapan Science and Technology Agency (JST)
  • Shoko Miura
    • Department of Obstetrics and Gynaecology Nagasaki University Graduate School of Biomedical Sciences
    • SORSTJapan Science and Technology Agency (JST)
  • Takako Shimada
    • Department of Obstetrics and Gynaecology Nagasaki University Graduate School of Biomedical Sciences
  • Kentaro Yamasaki
    • Department of Obstetrics and Gynaecology Nagasaki University Graduate School of Biomedical Sciences
  • Atsushi Yoshida
    • Department of Obstetrics and Gynaecology Nagasaki University Graduate School of Biomedical Sciences
  • Daisuke Nakayama
    • Department of Obstetrics and Gynaecology Nagasaki University Graduate School of Biomedical Sciences
  • Yoshisada Shibata
    • Department of Radiation Epidemiology Nagasaki University Graduate School of Biomedical Sciences
  • Norio Niikawa
    • Department of Human Genetics Nagasaki University Graduate School of Biomedical Sciences
    • SORSTJapan Science and Technology Agency (JST)
  • Hideaki Masuzaki
    • Department of Obstetrics and Gynaecology Nagasaki University Graduate School of Biomedical Sciences
Short Report

DOI: 10.1007/s00439-007-0356-9

Cite this article as:
Miura, K., Yoshiura, K., Miura, S. et al. Hum Genet (2007) 121: 631. doi:10.1007/s00439-007-0356-9

Abstract

Here we provided the first genetic evidence for an association between the degree of apocrine colostrum secretion and human earwax type. Genotyping at the earwax-type locus, rs17822931 within the ABCC11 gene, revealed that 155 of 225 Japanese women were dry-type and 70 wet-type. Frequency of women without colostrum among dry-type women was significantly higher than that among wet-type women (< 0.0002), and the measurable colostrum volume in dry-type women was significantly smaller than in wet-type women (P = 0.0341).

Keywords

Human earwax-type Colostrum secretion ABCC11 Polymorphism

Copyright information

© Springer-Verlag 2007