Original Paper

Parasitology Research

, Volume 112, Issue 8, pp 2839-2845

Anthelmintic efficacy of Santalum album (Santalaceae) against monogenean infections in goldfish

  • Xiao TuAffiliated withCollege of Animal Science and Technology, Northwest A&F University
  • , Fei LingAffiliated withCollege of Animal Science and Technology, Northwest A&F University Email author 
  • , Aiguo HuangAffiliated withCollege of Animal Science and Technology, Northwest A&F University
  • , Qizhong ZhangAffiliated withKey Laboratory of Aquatic Eutrophication and Control of Harmful Algal Blooms of Guangdong Higher Education Institutes, Engineering Research Center of Tropical and Subtropical Aquatic Ecological Engineering Minister of Education, Institute of Hydrobiology, Jinan University
  • , Gaoxue WangAffiliated withCollege of Animal Science and Technology, Northwest A&F University Email author 

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Abstract

Dactylogyrus spp. and Gyrodactylus spp. are helminth ectoparasites that are a significant threat to the aquaculture industry. Existing treatments could cause the threats of anthelmintic resistance, risk of residues, environmental contamination, and toxicity to fish. Importantly, there is no report on a treatment against these two parasites. This study explored the possibility of using the extracts of Santalum album to treat Dactylogyrus sp. and Gyrodactylus sp. infections in goldfish. Results showed that among the four extracts (chloroform, methanol, ethyl acetate, and water) of S. album, the chloroform extract is the most effective and 40 mg/L is a safe and the lowest effective dosage. In addition, we found that Gyrodactylus elegans is more sensitive than Dactylogyrus intermedius when exposed to the extract of the medicinal plant. Finally, it is substantiated that bath treatment with long duration and multiple administrations could eliminate a greater proportion of monogenean infections. These findings show the potential for the development of effective and safe therapy to treat Dactylogyrus sp. and Gyrodactylus sp. infections of fishes.