European Journal of Pediatrics

, Volume 170, Issue 9, pp 1107–1110

Subcutaneous fat necrosis in newborn—an unusual case and review of literature

Authors

    • Clinical Research Fellow in Neonatology, Addenbrooke’s HospitalCambridge University Hospitals NHS Trust
  • Jennifer Dove
    • Histopathology UnitLuton and Dunstable Hospital NHS Trust
  • Sateesh Kumar Somisetty
    • Neonatal UnitLuton and Dunstable Hospital NHS Trust
Review

DOI: 10.1007/s00431-011-1405-x

Cite this article as:
Mitra, S., Dove, J. & Somisetty, S.K. Eur J Pediatr (2011) 170: 1107. doi:10.1007/s00431-011-1405-x

Abstract

Subcutaneous fat necrosis (SCFN) of the newborn is an uncommon, self-limiting panniculitis mostly occurring within the first few weeks after birth. SCFN has been described mostly in term or post-term newborn infants in literature. We report a preterm infant developing extensive subcutaneous fat necrosis within the first week of life after significant perinatal hypoxic injury. The infant was conservatively managed for subcutaneous fat necrosis but developed hypercalcaemia and required prolonged medical treatment. Hypercalcaemia is a rare but serious complication of subcutaneous fat necrosis and needs prolonged follow-up. The etiopathogenesis of both subcutaneous fat necrosis in newborn and the resultant hypercalcaemia are poorly understood. Conclusion: Significant subcutaneous fat necrosis can develop in both preterm and term infants, and preterm infants also develop significant complications including hypercalcaemia.

Keywords

Subcutaneous fat necrosis of newbornHypercalcaemiaPerinatal hypoxiaHypoglycaemia

Copyright information

© Springer-Verlag 2011