European Journal of Pediatrics

, Volume 169, Issue 12, pp 1439–1444

EPONYM

Sweet syndrome

Authors

  • Mi Jin Kim
    • Department of PediatricsSamsung Medical Center, Sungkyunkwan University School of Medicine
    • Department of PediatricsSamsung Medical Center, Sungkyunkwan University School of Medicine
Review

DOI: 10.1007/s00431-010-1201-z

Cite this article as:
Kim, M.J. & Choe, Y.H. Eur J Pediatr (2010) 169: 1439. doi:10.1007/s00431-010-1201-z

Abstract

Sweet syndrome, also referred to as acute febrile neutrophilic dermatosis, is characterized by tender, red inflammatory nodules or papules that occur in association with infection, malignancy, connective tissue disease, or following exposure to certain drugs. Although drug-induced Sweet syndrome is rare, granulocyte colony-stimulating factor, all-trans-retinoic acid, and miscellaneous drugs have been implicated in causing this disorder in adults. In pediatric patients, granulocyte colony-stimulating factor, all-trans-retinoic acid, trimethoprim-sulfamethoxazole, and azathioprine have been implicated as potential causes of drug-induced Sweet syndrome. To date, six cases, including the patient reported here, have been reported in children.

Keywords

Sweet syndrome Drug induced Children

Abbreviations

SS

Sweet syndrome

c-ANCA

c-type anti-neutrophil cytoplasmic antibody

TPMT

Thiopurine methyltransferase

GCSF

Granulocyte colony-stimulating factor

Copyright information

© Springer-Verlag 2010