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Effectiveness of pamidronate in severe neonatal hypercalcemia caused by subcutaneous fat necrosis: a case report

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Abstract

Subcutaneous fat necrosis of the newborn (SCFN) is a panniculitis that develops in fatty areas during the first weeks of life after foetal distress or perinatal complications. Prognosis is generally good with complete regression, but it can be complicated by metabolic abnormalities like hypoglycemia, hypertriglyceridemia, thrombocytopenia, and also potentially life-threatening hypercalcemia. We report a case of severe hypercalcemia complicating SCFN in a newborn who was treated with hyperhydration, furosemide, prednisone, and pamidronate.

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Abbreviations

SCFN:

Subcutaneous fat necrosis of the newborn

SN:

Sclerema neonatorum

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Authors and Affiliations

  1. Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

    G. Lombardi, R. Cabano, L. Bollani & M. Stronati

  2. Institute of Dermatology, University of Pavia, Pavia, Italy

    C. Del Forno

Authors
  1. G. Lombardi
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  2. R. Cabano
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  3. L. Bollani
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  4. C. Del Forno
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  5. M. Stronati
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Correspondence to R. Cabano.

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Lombardi, G., Cabano, R., Bollani, L. et al. Effectiveness of pamidronate in severe neonatal hypercalcemia caused by subcutaneous fat necrosis: a case report. Eur J Pediatr 168, 625–627 (2009). https://doi.org/10.1007/s00431-008-0797-8

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  • DOI: https://doi.org/10.1007/s00431-008-0797-8

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