References
Zidar N, Gale N (2015). Carcinosarcoma and spindle cell carcinoma—monoclonal neoplasms undergoing epithelial-mesenchymal transition. Virchows Arch in this issue
Thiery JP, Sleeman JP (2006) Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7:131–142
Guarino M, Rubino B, Ballabio G (2007) The role of epithelial-mesenchymal transition in cancer pathology. Pathology 39:305–318
Tarin D, Thompson EW, Newgreen DF (2005) The fallacy of epithelial mesenchymal transition in neoplasia. Cancer Res 65:5996–6000
Paniz-Mondolfi A, Singh R, Jour G, Mahmoodi M, Hafeez Diwan A, Barkoh BA, Cason R, Huttenbach Y, Benaim G, Galbincea J, Luthra R (2014) Cutaneous carcinosarcoma: further insights into its mutational landscape through massive parallel genome sequencing. Virchows Arch 465:339–350
Paniz Mondolfi AE, Jour G, Johnson M, Reidy J, Cason RC, Barkoh BA, Benaim G, Singh R, Luthra R (2013) Primary cutaneous carcinosarcoma: insights into its clonal origin and mutational pattern expression analysis through next-generation sequencing. Hum Pathol 44:2853–2860
Grille SJ, Bellacosa A, Upson J (2003) The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Res 63:2172–2178
Jechlinger M, Sommer A, Moriggl R, Seither P, Kraut N, Capodiecci P, Donovan M, Cordon-Cardo C, Beug H, Grünert S (2006) Autocrine PDGFR signaling promotes mammary cancer metastasis. J Clin Invest 116:1561–1570
Conflict of interest
The authors declare that they have no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Paniz-Mondolfi, A., Singh, R., Jour, G. et al. Cutaneous carcinosarcoma and the EMT: to transition, or not to transition? That is the question. Virchows Arch 466, 359–360 (2015). https://doi.org/10.1007/s00428-015-1718-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00428-015-1718-7