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Effect of sleep efficiency on salivary metabolite profile and cognitive function during exercise in volleyball athletes

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European Journal of Applied Physiology Aims and scope Submit manuscript

Abstract

Purpose

Sleep duration is known to affect physiological and circadian metabolites and human homeostasis. However, little is known about the relationship between sleep quality and metabolite and cognitive function during exercise. Therefore, the aim of the present study was to investigate the impact of sleep quality on metabolite level and cognitive function in female volleyball athletes.

Methods

Twelve female volleyball athletes participated in this study. Sleep efficiency was measured for 1 week using NemuriSCAN (Paramount Bed Co. Ltd., Japan) as an index of sleep quality. The subjects were divided into better (n = 6) and lesser (n = 6) sleep quality groups by the median value of sleep efficiency. Saliva samples were collected using a Salimetric oral swab cotton and salivary metabolites were analysed using capillary electrophoresis and time-of-flight mass spectrometry. The subjects performed Stroop tasks (simple and difficult tasks) at rest and during aerobic exercise in recumbent cycle ergometer at light and heavy intensity.

Results

Increased sleep efficiency was found in the better sleep quality group, whereas total sleep time was similar. There were differences in urea cycle and Krebs cycle metabolites between the two groups; their levels were correlated with sleep efficiency. The difficult-task response time during heavy exercise was faster in the better sleep quality group.

Conclusion

We demonstrated that sleep efficiency was associated with urea cycle and Krebs cycle metabolite levels and response time during heavy exercise in volleyball athletes. These results suggested that sleep quality may affect amino acid and energy metabolism and cognitive function during heavy exercise.

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Abbreviations

CE-TOFMS:

Capillary electrophoresis and time-of-flight mass spectrometry

HRR:

Heart rate reserve

NO:

Nitric oxide

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Funding

This study was supported by the Japan Society for the Promotion of Science KAKENHI, Grant Number 26282181.

Author information

Authors and Affiliations

  1. Department of Sport Sciences, Japan Institute of Sport Sciences, 3-15-1 Nishigaoka, Kita-ku, Tokyo, Japan

    Nobuhiko Akazawa

  2. Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8574, Japan

    Nobuhiko Akazawa, Hiroshi Kumagai, Youngju Choi & Seiji Maeda

  3. Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

    Naoko Kobayashi & Yuki Nakamura

  4. Graduate School of Health and Sports Science, Juntendo University, 1-1 Hiraga-gakuendai, Inzai, Chiba, Japan

    Hiroshi Kumagai

  5. Japan Society for the Promotion of Science, 5-3-1 Koji-machi, Chiyoda-ku, Tokyo, Japan

    Hiroshi Kumagai

Authors
  1. Nobuhiko Akazawa
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  2. Naoko Kobayashi
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  3. Yuki Nakamura
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  4. Hiroshi Kumagai
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  5. Youngju Choi
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  6. Seiji Maeda
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Contributions

NA and SM conceived and designed research. NA and NK conducted experiments. NA, NK, YN, HK, and YC collected and analyzed data. NA wrote the manuscript. All authors read and approved the manuscript.

Corresponding author

Correspondence to Seiji Maeda.

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The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Communicated by Philip D. Chilibeck.

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Akazawa, N., Kobayashi, N., Nakamura, Y. et al. Effect of sleep efficiency on salivary metabolite profile and cognitive function during exercise in volleyball athletes. Eur J Appl Physiol 119, 2215–2223 (2019). https://doi.org/10.1007/s00421-019-04205-7

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  • DOI: https://doi.org/10.1007/s00421-019-04205-7

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