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Recurrence rate and subjective symptoms after standardized (Hamburg protocol) phototherapeutic keratectomy on recurrent corneal erosions

  • Cornea
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Abstract

Purpose

To evaluate the objective and subjective outcome after phototherapeutic keratectomy (PTK) on recurrent corneal erosions (Hamburg protocol).

Methods

For the standardized PTK according to Hamburg protocol a manual abrasio corneae performed with 20 % alcohol is followed by an excimer ablation depth of ≥15 μm (group1 15 μm; group 2 > 15 μm ablation depth) and 7 mm optical zone. All patients (N = 48) were invited for follow-up examinations and the evaluation of changes concerning subjective symptoms.

Results

A significantly reduced subjective impairment of night vision, significantly less pain and less foreign body sensations (for all p < 0.05) were noted in 48 patients that met the inclusion criteria (26 women, 22 men). In the follow-up period an improvement of corrected distance visual acuities (cdva) from 0.80 to 1.08 (group 1) and from 0.58 to 0.99 (group 2) was demonstrated.

Conclusion

PTK (Hamburg Schema) is a safe and effective procedure to reduce subjective symptoms and improve discomfort in recurrent corneal erosion.

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Author notes

    Authors and Affiliations

    1. Clinic of Ophthalmology, Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany

      J. Mehlan, L. Traber, T. Katz & S. J. Linke

    2. zentrumsehstärke, Hamburg, Germany

      J. Steinberg & S. J. Linke

    3. CareVision Hamburg, Hamburg, Germany

      J. Steinberg, T. Katz & S. J. Linke

    4. Universitäts-Augenklinik Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany

      J. Steinberg

    Authors
    1. J. Mehlan
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    2. J. Steinberg
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    3. L. Traber
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    4. T. Katz
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    5. S. J. Linke
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    Corresponding author

    Correspondence to J. Steinberg.

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    Funding

    No funding was received for this research.

    Conflict of interest

    All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this manuscript.

    Ethical approval

    All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

    Informed consent

    Informed consent was obtained from all individual participants included in the study.

    Additional information

    J. Mehlan and J. Steinberg contributed equally to this work.

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    Mehlan, J., Steinberg, J., Traber, L. et al. Recurrence rate and subjective symptoms after standardized (Hamburg protocol) phototherapeutic keratectomy on recurrent corneal erosions. Graefes Arch Clin Exp Ophthalmol 254, 2005–2009 (2016). https://doi.org/10.1007/s00417-016-3470-3

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    • DOI: https://doi.org/10.1007/s00417-016-3470-3

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