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Six-month visual prognosis in eyes with submacular hemorrhage secondary to age-related macular degeneration or polypoidal choroidal vasculopathy

  • Retinal Disorders
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

Background

To determine clinical or imaging prognostic features for visual outcome in eyes with submacular hemorrhage secondary to age-related macular degeneration (AMD) or polypoidal choroidal vasculopathy (PCV).

Methods

A prospective case series of 11 eyes from 11 patients with submacular hemorrhage secondary to AMD or PCV. All participants had measurement of clinical characteristics, fundus angiogram, and indocyanine green angiography, spectral domain optical coherence tomography (OCT, Cirrus, Zeiss) at baseline and 6 months.

Results

Median visual acuity improved from 20/132 to 20/63 at month 6. The median improvement in vision was 0.20 LogMAR units. Proportion of eyes with best-corrected visual acuity (BCVA) ≥1.0 increased from 6/11 (54.5 %) at baseline to 8/11 (72.7 %) at month 6. Eyes with BCVA > 1.0 were more likely to have larger area of hemorrhage and thinner subfoveal neurosensory retinal thickness at baseline and at month 6.

Conclusions

Thinner neurosensory retina demonstrated on OCT at baseline may be a useful prognostic sign for limited visual recovery.

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Acknowledgments

Funding: This study was supported by National Medical Research Council grant NMRC/NIG/1003/2009.

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Authors and Affiliations

  1. Singapore National Eye Centre, Singapore, Singapore

    Chui Ming Gemmy Cheung, Mayuri Bhargava, Ranjana Mathur, Chan Choi Mun, Doric Wong & Tien Yin Wong

  2. Singapore Eye Research Institute, Singapore, Singapore

    Chui Ming Gemmy Cheung, Mayuri Bhargava, Li Xiang & Tien Yin Wong

  3. Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

    Chui Ming Gemmy Cheung, Mayuri Bhargava & Tien Yin Wong

  4. Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia

    Tien Yin Wong

Authors
  1. Chui Ming Gemmy Cheung
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  2. Mayuri Bhargava
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  3. Li Xiang
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  4. Ranjana Mathur
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  5. Chan Choi Mun
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  6. Doric Wong
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  7. Tien Yin Wong
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Corresponding author

Correspondence to Chui Ming Gemmy Cheung.

Additional information

Financial disclosure: GC – none, MB – none, LX – none, RM – none, CCM – none, DW – none, TYW – none.

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Cheung, C.M.G., Bhargava, M., Xiang, L. et al. Six-month visual prognosis in eyes with submacular hemorrhage secondary to age-related macular degeneration or polypoidal choroidal vasculopathy. Graefes Arch Clin Exp Ophthalmol 251, 19–25 (2013). https://doi.org/10.1007/s00417-012-2029-1

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  • DOI: https://doi.org/10.1007/s00417-012-2029-1

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