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Clinical characteristics of ocular toxocariasis in Eastern China

  • Inflammatory Disorders
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Abstract

Purpose

To explore the clinical characteristics of patients with ocular toxocariasis in eastern China.

Methods

The medical records of 35 cases of ocular toxocariasis in Fudan University Eye & ENT Hospital between May 2009 and April 2011 were retrospectively reviewed and analyzed. UBM, RetCam or fundus imaging, and high-frequency or conventional ultrasonography were performed in these patients.

Results

The mean patient age in our series of ocular toxocariasis was 11.86 ± 8.80 years. There were 28 children and seven adults, the majority residing in a rural area (88.57%). All cases were classified into three clinical subtypes: granuloma in the peripheral retina (60% of cases); granuloma in the posterior pole (28.57% of cases); and vitreous inflammation mimicking chronic endophthalmitis (5.71% of cases). We also identified an additional subtype with unique clinical features that we termed “combined type” presenting in 5.71% of our patients. This subtype exhibited granulomas in both the posterior pole and peripheral retina. RetCam fundus imaging was able to identify granulomas in the posterior and peripheral subtypes, 100% and 80.95% of cases respectively. Moreover, UBM combined with conventional ultrasonography identified granulomas in 95% of the peripheral subtype cases and in 100% of the posterior pole subtype cases.

Conclusions

This is the first ocular toxocariasis series described in Chinese patients. Compared with reports from developed countries, the ocular features in our series were more severe and complicated, presenting with poorer visual acuity and a high rate of retinal detachment (45.7%). The application of RetCam and UBM during examination in ocular toxocariasis can provide valuable information in determining the severity of disease and features important in considering surgical procedures in such patients.

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Conflict of Interest

None of the authors have any financial /conflicting interests to disclose.

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Authors and Affiliations

  1. Department of Ophthalmology, Fudan University Eye and ENT Hospital, Fudan University, 83 Fenyang Rd, Shanghai, China

    Min Zhou, Qing Chang, Qian Chen, Yanqiong Zhang, Xin Huang, Gezhi Xu, Wenji Wang & Rui Jiang

  2. The Francis I. Proctor Foundation and the Department of Ophthalmology, University of California at San Francisco, 954 Kirkham Street, Box 0944, San Francisco, CA, 94143-0944, USA

    John A. Gonzales

Authors
  1. Min Zhou
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  2. Qing Chang
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  3. John A. Gonzales
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  4. Qian Chen
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  5. Yanqiong Zhang
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  6. Xin Huang
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  7. Gezhi Xu
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  8. Wenji Wang
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  9. Rui Jiang
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Corresponding author

Correspondence to Rui Jiang.

Additional information

Min Zhou and Qing Chang contributed equally to the manuscript.

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Zhou, M., Chang, Q., Gonzales, J.A. et al. Clinical characteristics of ocular toxocariasis in Eastern China. Graefes Arch Clin Exp Ophthalmol 250, 1373–1378 (2012). https://doi.org/10.1007/s00417-012-1971-2

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  • DOI: https://doi.org/10.1007/s00417-012-1971-2

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