Journal of Neurology

, Volume 258, Issue 8, pp 1513–1517

How well do we recognise non-motor symptoms in a British Parkinson’s disease population?

Authors

    • Department of NeurologyMilton Keynes Hospital NHS Foundation Trust and Oxford Radcliffe Hospitals
    • Department of Clinical NeurologyLevel 3, West Wing, John Radcliffe Hospital
  • Jonathan Cooper
    • Department of General MedicineMilton Keynes Hospital NHS Foundation Trust
  • Rebecca Beamish
    • Department of General MedicineMilton Keynes Hospital NHS Foundation Trust
  • Emma Jones
    • Milton Keynes Neuro-Rehabilitation Unit
  • Richard Butterworth
    • Department of NeurologyMilton Keynes Hospital NHS Foundation Trust and Oxford Radcliffe Hospitals
  • Lesley Catterall
    • Thames Valley Dementia and Neurodegenerative Diseases Research Network (DeNDRoN)
  • Yoav Ben-Shlomo
    • Department of Social MedicineUniversity of Bristol
Original Communication

DOI: 10.1007/s00415-011-5972-6

Cite this article as:
Hu, M., Cooper, J., Beamish, R. et al. J Neurol (2011) 258: 1513. doi:10.1007/s00415-011-5972-6

Abstract

Although awareness of non-motor symptoms in Parkinson’s disease (PD) has recently increased, little is known about their recognition and treatment in routine clinical practice. We therefore applied non-motor rating scales for dementia, depression, anxiety and excessive daytime sleepiness to a community-ascertained cohort of 202 PD patients. Hospital case notes were reviewed for evidence that the non-motor problems had been recognized and whether any action had been taken to ameliorate or assess these symptoms. The prevalence of each non-motor problem was as follows: dementia 25.3% (95% CI 19.0, 32.4), depression 37.3% (95% CI 30.6, 44.4), anxiety 31.3% (95% CI 25.0, 38.2), excessive daytime sleepiness 59.4% (95% CI 52.2, 66.3). However, these features were only recognised in 27.2, 38.7, 9.5, and 12.8%, respectively. We did not identify any specific factor that predicted under-recognition. Our study shows that when rating scales are applied to formally assess for non-motor symptoms a large clinical ‘iceberg effect’ emerges with the majority of symptoms going unrecognised and untreated.

Keywords

Parkinson’s diseaseNon-motor symptomsRecognition

Copyright information

© Springer-Verlag 2011