Original Communication

Journal of Neurology

, Volume 258, Issue 4, pp 596-602

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

Weather sensitivity in migraineurs

  • Jan HoffmannAffiliated withDepartment of Neurology, Charité-Universitätsmedizin BerlinDepartment of Neurology, University of California, San Francisco
  • , Hendra LoAffiliated withDepartment of Neurology, Charité-Universitätsmedizin Berlin
  • , Lars NeebAffiliated withDepartment of Neurology, Charité-Universitätsmedizin Berlin
  • , Peter MartusAffiliated withInstitute of Biometry and Clinical Epidemiology, Charité-Universitätsmedizin Berlin
  • , Uwe ReuterAffiliated withDepartment of Neurology, Charité-Universitätsmedizin Berlin Email author 


The scientific evidence for weather being a trigger factor for migraine attacks is inconclusive. We investigated the association between weather components and the onset and severity of attacks. Headache diaries of 20 migraineurs were analyzed retrospectively and correlated in 4-h intervals to atmospheric air pressure, temperature, and relative air humidity in Berlin (Germany) for a period of 12 consecutive months. Absolute values and relative changes within the preceding 24 h were analyzed. Migraine attacks started most frequently at 4 a.m. and reached the highest intensity between 4 and 8 a.m. A highly significant association between meteorological variables and the occurrence of migraine attacks was found in six patients. The onset of an attack as well as high headache intensity was associated with lower temperature and higher humidity. Our data indicate that a subgroup of migraineurs is highly sensitive to changes of certain weather components.


Migraine Weather Temperature Humidity Atmospheric pressure