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Population data of 23 STR loci (PowerPlex® Fusion System) in Mexican Mestizos from the West Region

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Abstract

We analyzed 238 unrelated Mestizo (admixed) individuals from the West region of Mexico with the PowerPlex® Fusion System (Promega Corp.). Allele frequencies and forensic parameters were estimated for the 23 STRs included in this kit. Hardy-Weinberg equilibrium by locus and non-association between pair of loci were demonstrated by exact tests in this population. The combined PE and PD offered by this HID kit were ≥0.9999999986, representing a substantial improvement with respect to those previously offered by 15 STR systems. Interpopulation comparison by AMOVA tests demonstrated low but significant differences among Mexican Mestizos from West, Center, and Northeast regions (Fst = 0.01558; p = 0.0000), similar to the observed among three main ethnic groups from USA (Fst = 0.02048; p = 0.0000). This finding is consistent with the contrary clines of European and Amerindian ancestries described throughout the Mexican territory for Mestizos, the largest population (~90 %) in this country.

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Acknowledgments

We thank the technical support of the QFB, Juan Páez, and the partial financial support to this project of Distribuidora Comercial Zogbi S.A. de C.V (Ing. Jorge Zogbi). We thank to CONACyT for the fellowship to JAA-V.

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Authors and Affiliations

  1. Instituto de Investigación en Genética Molecular, Centro Universitario de la Ciénega, Universidad de Guadalajara (CUCiénega-UdeG), Av. Universidad #1115, Col. Paso Blanco, Ocotlán, Jalisco, CP 47810, Mexico

    J. A. Aguilar-Velázquez, G. Martínez-Cortés & H. Rangel-Villalobos

  2. Laboratorio de Genética Forense, Procuraduría de Justicia del Distrito Federal, México, DF, Mexico

    A. Inclán-Sánchez

  3. Laboratorio DNA Profile SC, Jamaica 90, El Rosario, Ocotlán, Jalisco, Mexico

    O. Romero-Rentería, X. X. Díaz-Navarro & H. Rangel-Villalobos

Authors
  1. J. A. Aguilar-Velázquez
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  2. G. Martínez-Cortés
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  3. A. Inclán-Sánchez
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  4. O. Romero-Rentería
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  5. X. X. Díaz-Navarro
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  6. H. Rangel-Villalobos
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Corresponding author

Correspondence to H. Rangel-Villalobos.

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Samples of buccal swabs or blood spotted on FTA® cards were obtained under personal informed consent from volunteer donors according to the principles outlined in the Helsinki Declaration.

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Fig. S1

Geographic location and sample size (n) of the studied Mexican-Mestizo populations, plus those previously analyzed (*) (GIF 68 kb)

High Resolution Image (TIF 1961 kb)

Table S1

STR genotype database (XLSX 58 kb)

Table S2

(DOCX 31 kb)

Table S3

(DOCX 18 kb)

Table S4

(DOCX 16 kb)

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Aguilar-Velázquez, J.A., Martínez-Cortés, G., Inclán-Sánchez, A. et al. Population data of 23 STR loci (PowerPlex® Fusion System) in Mexican Mestizos from the West Region. Int J Legal Med 130, 1489–1491 (2016). https://doi.org/10.1007/s00414-016-1361-0

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  • DOI: https://doi.org/10.1007/s00414-016-1361-0

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