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Analysis of 27 Y-chromosomal STR haplotypes in a Han population of Henan province, Central China

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Abstract

A total of 1225 unrelated Han males from Henan province were analyzed with the prototype Yfiler® Plus kit (Life Technologies, Thermo Fisher Scientific, Waltham, MA, USA). The calculated gene diversity (GD) values ranged from 0.3855 to 0.9673 for the DYS391 and DYS385a/b loci, respectively. The discriminatory capacity (DC) was 86.94 % with 1065 observed haplotypes using 17 Yfiler loci, by the addition of 10 Y-STRs to the Yfiler® Plus system, the DC was increased to 98.94 % while showing 1212 observed haplotypes. Among the new incorporated Y-STRs, DYS576, DYF387S1, DYS518, DYS627, and DYS449 were major contributors to enhancing discrimination. In the analysis of molecular variance, the Henan Han population clustered with Asian origin populations and showed significant differences from other reference populations. In this study, the improvement of adding additional Y-STR markers with the Yfiler® Plus kit provided substantially stronger discriminatory power in the Henan Han population.

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Acknowledgments

We thank all sample donors for their contributions to this work and all those who helped with sample collection. This study was supported by The National Natural Science Foundation of China (NSFC. Nos. 81172902, 81471821, and 81373745), the Program for New Century Excellent Talents in University (No.NCET-10-0773), the China Postdoctoral Science Foundation funded project (No.2013 M530371), and the Collaborative Innovation Center of Judicial Civilization, China.

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Authors and Affiliations

  1. Key Laboratory of Evidence Science (China University of Political Science and Law), Ministry of Education, 25 Xitucheng Road, Beijing, 100088, People’s Republic of China

    Rufeng Bai, Meisen Shi, R. F. Bai & MS. Shi

  2. Collaborative Innovation Center of Judicial Civilization, 25 Xitucheng Road, Beijing, 100088, People’s Republic of China

    Rufeng Bai, Meisen Shi, R. F. Bai & MS. Shi

  3. Xuchang Institute of Forensic Sciences, Public Security Bureau of Henan Province, Henan, 461000, People’s Republic of China

    Yaju Liu & Juntao Zhang

  4. Department of Forensic Medicine, Huazhong University of Science and Technology, Tongji Medical College, Hubei, 430030, People’s Republic of China

    Hongmei Dong

  5. Department of Radiology, First Affiliated Hospital, Medical College of Shantou University, Shantou, 515041, People’s Republic of China

    Shuhua Ma

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  1. Rufeng Bai
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  2. Yaju Liu
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  3. Juntao Zhang
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  4. Meisen Shi
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  5. Hongmei Dong
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  6. Shuhua Ma
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  7. R. F. Bai
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  8. MS. Shi
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Corresponding authors

Correspondence to Hongmei Dong or Shuhua Ma.

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Bai, R., Liu, Y., Zhang, J. et al. Analysis of 27 Y-chromosomal STR haplotypes in a Han population of Henan province, Central China. Int J Legal Med 130, 1191–1194 (2016). https://doi.org/10.1007/s00414-016-1326-3

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  • DOI: https://doi.org/10.1007/s00414-016-1326-3

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