Technical Note

International Journal of Legal Medicine

, Volume 122, Issue 3, pp 245-249

First online:

Detection of ethyl glucuronide in dried human blood using LC-MS/MS

  • Eckhard KaufmannAffiliated withDepartment of General Physiology, University of UlmInstitute for Laser Technology in Medicine Email author 
  • , Andreas AltAffiliated withDepartment of Forensic Medicine, University of Ulm

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Ethyl glucuronide, as a direct metabolite of ethanol degradation, has proven useful as a long-term marker in many forensic applications. The inability to determine ethyl glucuronide in dried blood left a missing link in many investigations. Here, we describe a new method based on mass spectrometry in a Pauli-type ion trap in order to determine this substance in dried blood samples.


Ethanol Ethyl glucuronide LC/MS Ion trap