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Retrospective evaluation of borderline ovarian tumors: single center experience of 183 cases

  • Gynecologic Oncology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Purpose

Borderline ovarian tumors (BOTs) constitute about a quarter of epithelial ovarian malignancies and require different treatment approaches. The present study aims to document the experience of a single center on the treatment outcome of women who had conservative or comprehensive surgery for BOTs.

Methods

One hundred eighty-three patients with BOTs, diagnosed and/or treated in our center between January of 2000 and March of 2013, were reviewed retrospectively.

Results

The mean age at diagnosis was 40.6 years old (range 17–78). Ninety-five patients (51 %) were ≤40 years. Comprehensive surgical staging and fertility sparing surgery were performed in 49 % (n = 91) and 48 % of patients (n = 89) respectively. A hundred and forty-seven patients had stage IA disease (80 %). The most common type of BOT was serous in histology with 18 % bilateralism. CA-125 and CA-199 levels were increased in 29 (19 %) and 15 (10 %) patients with stage IA disease. Non-invasive tumor implants were diagnosed in 9 patients (4 %) and uterine involvement was 2 % among BOT patients that underwent hysterectomies. The mean post-operative follow-up period was 20.4 months (range 6–78 months). Disease recurrence was seen in 5 patients indicating overall recurrence rate of 2.7 %.

Conclusions

In our study, we evaluated a large data pool of 183 patients diagnosed with borderline epithelial ovarian tumors. BOTs have a relatively better prognosis than invasive epithelial ovarian cancer. Surgery with proper staging is the cornerstone of treatment. Patients with BOTs at the early stage can undergo fertility sparing surgery with close follow-up.

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Gynecologic Oncology, Zekai Tahir Burak Women’s Health Education and Research Hospital, 06230, Hamamonu, Ankara, Turkey

    Tayfun Gungor, Nilufer Cetinkaya, Hakan Yalcin, Bulent Ozdal, Emre Ozgu, Eralp Baser, Dilek Uygur & Salim Erkaya

  2. Department of Obstetrics and Gynecology, Düzce University School of Medicine, Düzce, Turkey

    Mete Caglar

  3. Department of Pathology, Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara, Turkey

    Levent Sirvan

Authors
  1. Tayfun Gungor
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  2. Nilufer Cetinkaya
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  3. Hakan Yalcin
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  4. Bulent Ozdal
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  5. Emre Ozgu
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  6. Eralp Baser
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  7. Dilek Uygur
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  8. Mete Caglar
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  9. Levent Sirvan
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  10. Salim Erkaya
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Corresponding author

Correspondence to Nilufer Cetinkaya.

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Gungor, T., Cetinkaya, N., Yalcin, H. et al. Retrospective evaluation of borderline ovarian tumors: single center experience of 183 cases. Arch Gynecol Obstet 291, 123–130 (2015). https://doi.org/10.1007/s00404-014-3381-7

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  • DOI: https://doi.org/10.1007/s00404-014-3381-7

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