Skip to main content
Log in

Clinical significance of ptyalism gravidarum

  • Maternal-Fetal Medicine
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Objective

The aim of this study was to identify the clinical significance associated with ptyalism gravidarum in Japanese singleton pregnancies.

Methods

Data were collected from 22 patients complicated by ptyalism gravidarum whose symptoms continued until delivery and from 7,743 unaffected controls.

Results

The incidence of ptyalism gravidarum in the Japanese pregnant women was about 0.3 %. Using multiple logistic regressions, ptyalism gravidarum was associated with history of hyperemesis gravidarum (p < 0.01), neonatal male sex (p = 0.02) and small for gestational age infants (p = 0.04).

Conclusions

Ptyalism gravidarum may be a distinctive condition leading to adverse perinatal outcomes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Bemstine RL, Friedman MHF (1957) Salivation in pregnant and non-pregnant women. Obstet Gynecol 10:184–189

    Google Scholar 

  2. Elsmén E, Källén K, Maršál K, Hellström-Westas L (2006) Fetal gender and gestational-age-related incidence of pre-eclampsia. Acta Obstet Gynecol Scand 85:1285–1291

    Article  PubMed  Google Scholar 

  3. Erick M (1988) Ptyalism gravidarum: an unpleasant reality (Letter to the editors). J Am Diet Assoc 98:129

    Article  Google Scholar 

  4. Freeman JJ, Altieri RH, Baptiste HJ, Kao T, Crittenden S, Fogarty K, Moultrie M, Coney E, Kangis K (1994) Evaluation and management of sialorrhea of pregnancy with concomitant hyperemesis. J Natl Med Assoc 86:704–708

    PubMed  CAS  Google Scholar 

  5. Gross S, Librach C, Cerutti A (1989) Maternal weight loss associated with hyperemesis gravidarum: a predictor of fetal outcome. Am J Obstet Gynecol 160:906–909

    PubMed  CAS  Google Scholar 

  6. Lorzadeh N, Kazemirad S (2012) The effects of fetal gender on serum human chorionic gonadotropin and testosterone in normotensive and preeclamptic pregnancies. J Pregnancy 2012:874290

    PubMed  Google Scholar 

  7. Mandel L, Tamari K (1995) Sialorrhea and gastroesophageal reflux. J Am Dent Assoc 126:1537–1541

    PubMed  CAS  Google Scholar 

  8. Murji A, Proctor LK, Paterson AD, Chitayat D, Weksberg R, Kingdom J (2012) Male sex bias in placental dysfunction. Am J Med Genet 158A:779–783

    Article  PubMed  Google Scholar 

  9. Rice H (1951) Ptyalism during pregnancy (Letter to the editor). JAMA 146:1545–1546

    Google Scholar 

  10. Suzuki S, Igarashi M, Yamashita E, Satomi M (2009) Ptyalism gravidarum. N Am J Med Sci 1:303–304

    PubMed  Google Scholar 

  11. Van Dinter MC (1991) Ptyalism in pregnant women. J Obstet Gynecol Neonatal Nurs 20:206–209

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

We declare that we have no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shunji Suzuki.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Suzuki, S., Fuse, Y. Clinical significance of ptyalism gravidarum. Arch Gynecol Obstet 287, 629–631 (2013). https://doi.org/10.1007/s00404-012-2614-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00404-012-2614-x

Keywords

Navigation