Gynecologic Oncology

Archives of Gynecology and Obstetrics

, Volume 285, Issue 1, pp 195-205

Cancer in pregnancy. Part I: basic diagnostic and therapeutic principles and treatment of gynecological malignancies

  • Friederike HoellenAffiliated withDepartment of Obstetrics and Gynecology, University Hospital of Schleswig–Holstein Email author 
  • , Roland ReibkeAffiliated withDepartment of Internal Medicine III; Klinikum Grosshadern, Ludwigs-Maximilians-University of Munich
  • , Katrin HornemannAffiliated withDepartment of Thoracic Surgery, Thoraxklinik, University of Heidelberg
  • , Marc ThillAffiliated withDepartment of Obstetrics and Gynecology, University Hospital of Schleswig–Holstein
  • , Doerte W. LueddersAffiliated withDepartment of Obstetrics and Gynecology, University Hospital of Schleswig–Holstein
  • , Katharina KellingAffiliated withDepartment of Obstetrics and Gynecology, University Hospital of Schleswig–Holstein
  • , Amadeus HornemannAffiliated withDepartment of Obstetrics and Gynecology, University Medical Center Mannheim, University of Heidelberg
  • , Michael K. BohlmannAffiliated withDepartment of Obstetrics and Gynecology, University Hospital of Schleswig–Holstein

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

Purpose

Cancer in pregnancy is a rare circumstance. However, the coincidence of pregnancy and malignancy is supposed to increase due to a general tendency of postponing childbearing to older age. To date, clinical guidelines are scarce and experience regarding therapeutic management is limited to case reports.

Methods

This review focuses on general diagnostic and therapeutic principles including systemic therapy for malignancies in pregnancy.

Results

In part I, we report on diagnosis and therapy of gynecological tumors.

Conclusion

The diagnosis of gestational cancer faces both oncologist and obstetrician to the dilemma of applying appropriate diagnostic techniques and adequate local and systemic therapy to an expectant mother without harming the fetus.

Keywords

Cancer Malignancy Pregnancy Chemotherapy Radiotherapy Fetus