Archives of Gynecology and Obstetrics

, Volume 285, Issue 1, pp 195–205

Cancer in pregnancy. Part I: basic diagnostic and therapeutic principles and treatment of gynecological malignancies

  • Friederike Hoellen
  • Roland Reibke
  • Katrin Hornemann
  • Marc Thill
  • Doerte W. Luedders
  • Katharina Kelling
  • Amadeus Hornemann
  • Michael K. Bohlmann
Gynecologic Oncology

DOI: 10.1007/s00404-011-2058-8

Cite this article as:
Hoellen, F., Reibke, R., Hornemann, K. et al. Arch Gynecol Obstet (2012) 285: 195. doi:10.1007/s00404-011-2058-8

Abstract

Purpose

Cancer in pregnancy is a rare circumstance. However, the coincidence of pregnancy and malignancy is supposed to increase due to a general tendency of postponing childbearing to older age. To date, clinical guidelines are scarce and experience regarding therapeutic management is limited to case reports.

Methods

This review focuses on general diagnostic and therapeutic principles including systemic therapy for malignancies in pregnancy.

Results

In part I, we report on diagnosis and therapy of gynecological tumors.

Conclusion

The diagnosis of gestational cancer faces both oncologist and obstetrician to the dilemma of applying appropriate diagnostic techniques and adequate local and systemic therapy to an expectant mother without harming the fetus.

Keywords

CancerMalignancyPregnancyChemotherapyRadiotherapyFetus

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Friederike Hoellen
    • 1
  • Roland Reibke
    • 2
  • Katrin Hornemann
    • 3
  • Marc Thill
    • 1
  • Doerte W. Luedders
    • 1
  • Katharina Kelling
    • 1
  • Amadeus Hornemann
    • 4
  • Michael K. Bohlmann
    • 1
  1. 1.Department of Obstetrics and GynecologyUniversity Hospital of Schleswig–HolsteinLuebeckGermany
  2. 2.Department of Internal Medicine III; Klinikum GrosshadernLudwigs-Maximilians-University of MunichMunichGermany
  3. 3.Department of Thoracic Surgery, ThoraxklinikUniversity of HeidelbergHeidelbergGermany
  4. 4.Department of Obstetrics and GynecologyUniversity Medical Center Mannheim, University of HeidelbergMannheimGermany