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The contribution of vitamin C to healing of experimental fractures

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Archives of Orthopaedic and Trauma Surgery Aims and scope Submit manuscript

Abstract

The benefits of various minerals and vitamins on fracture healing have been demonstrated in animal models. Vitamin C is an essential substance in fracture healing but has not been studied previously on an experimental basis. Sixteen rats were grouped randomly into control and vitamin C-supplemented groups. The right tibias of all rats were fractured by digital manipulation. One group received single high dose of vitamin C intramuscularly. On the 5th, 10th, 15th, and 20th days, two rats from each group were killed and the tibias examined under light microscopy. It was seen that the vitamin C-supplemented group went through the stages of fracture healing faster compared with the control group.

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Authors and Affiliations

  1. Department of Orthopedics and Traumatology, University of Ankara Medical School, Ankara, Turkey, , , , , , TR

    Cengiz Yilmaz, Hakan Selek, Hakan Kinik, Murat Arikan & Bülent Erdemli

  2. Department of Histology and Embryology, University of Ankara Medical School, Ankara, Turkey, , , , , , TR

    Esra Erdemli

Authors
  1. Cengiz Yilmaz
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  2. Esra Erdemli
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  3. Hakan Selek
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  4. Hakan Kinik
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  5. Murat Arikan
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  6. Bülent Erdemli
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Received: 15 May 2000

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Yilmaz, C., Erdemli, E., Selek, H. et al. The contribution of vitamin C to healing of experimental fractures. Arch Orth Traum Surg 121, 426–428 (2001). https://doi.org/10.1007/s004020100272

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  • DOI: https://doi.org/10.1007/s004020100272

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