Skip to main content

Advertisement

Log in

A case of isolated giant plexiform neurofibroma involving all branches of the common peroneal nerve

  • Orthopaedic Surgery
  • Published:
Archives of Orthopaedic and Trauma Surgery Aims and scope Submit manuscript

Abstract

Plexiform neurofibroma is generally considered as a component of neurofibromatosis 1, and a great majority of the cases with plexiform neurofibroma display other symptoms related to neurofibromatosis. Plexiform neurofibromas occur frequently in the head and neck region due to the rich innervation of the area, however appear rarely in the extremities. We report here an isolated giant plexiform neurofibroma involving the common peroneal nerve branches without symptoms related to neurofibromatosis in a 5-year-old case. Surgical excision was performed due to pain and numbness in the leg, and against the possibility of malignant transformation due to sudden growth observed in the tumor. One month following the excision of all the reachable tumoral tissues, tendon transfer surgery was performed for the ankle and toe extensions. Our case stands as the only reported case of isolated giant plexiform neurofibroma involving the common peroneal nerve in the pediatric age.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Korf BR Plexiform neurofibromas (1999) Am J Med Genet 26;89(1):31–37

  2. Crawford AH, Schorry EK (2006) Neurofibromatosis update. J Pediatr Orthop 26(3):413–423

    PubMed  Google Scholar 

  3. Lin V, Daniel S, Forte V (2004) Is a plexiform neurofibroma pathognomonic of neurofibromatosis type I? Laryngoscope 114(8):1410–1414

    Article  PubMed  Google Scholar 

  4. Packer RJ, Gutmann DH, Rubenstein A, Viskochil D, Zimmerman RA, Vezina G, Small J, Korf B (2002) Plexiform neurofibromas in NF1: toward biologic-based therapy. Neurology 28;58(10):1461–1470

    Google Scholar 

  5. Hope DG, Mulvihill JJ (1981) Malignancy in neurofibromatosis. Adv Neurol 29:33–56

    PubMed  CAS  Google Scholar 

  6. Lin J, Martel W (2001) Cross-sectional imaging of peripheral nerve sheath tumors: characteristic signs on CT, MR imaging, and sonography. AJR Am J Roentgenol 176(1):75–82

    PubMed  CAS  Google Scholar 

  7. Salazar F, Machado A, Murthy S, Boulis NM (2005 ) Thoracoscopically guided transaxillary resection of adjoining intercostal plexiform neurofibromas: review of mosaicism in neurofibromatosis: technical note. Neurosurgery 57(4 Suppl):E407; discussion E407

  8. Wise JB, Cryer JE, Belasco JB, Jacobs I, Elden L (2005) Management of head and neck plexiform neurofibromas in pediatric patients with neurofibromatosis type 1. Arch Otolaryngol Head Neck Surg 131(8):712–718

    Article  PubMed  Google Scholar 

  9. Pu LL, Vasconez HC (2004) Large recurrent plexiform neurofibroma of the foot and ankle. Microsurgery 24(1):67–71

    Article  PubMed  Google Scholar 

  10. Blitz NM, Hutchinson B, Grabowski MV (2002) Pedal plexiform neurofibroma: review of the literature and case report. J Foot Ankle Surg 41(2):117–124

    Article  PubMed  Google Scholar 

  11. Nagel A, Greenebaum E, Singson RD, Rosenwasser MP, McCann PD (1994) Foot drop in a long-distance runner. An unusual presentation of neurofibromatosis. Orthop Rev 23(6):526–530

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Oguz Cebesoy.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cebesoy, O., Tutar, E., İsik, M. et al. A case of isolated giant plexiform neurofibroma involving all branches of the common peroneal nerve. Arch Orthop Trauma Surg 127, 709–712 (2007). https://doi.org/10.1007/s00402-007-0303-1

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00402-007-0303-1

Keywords

Navigation