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Synthesis of multifunctional microspheres having polymer brush with magnetism, fluorescence, and pH-responsiveness

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Abstract

Multifunctional magnetite@silica-fluorescein isothioxylate-g-poly(dimethyl amino ethyl methacrylate) (Fe3O4@SiO2-FITC-g-PDMAEMA) tri-layer microspheres with magnetism, fluorescence, and pH-responsive PDMAEMA shell were designed and prepared. The functional PDMAEMA brush was grafted from Fe3O4@SiO2-FITC nanoparticles by the surface-induced atom transfer radical polymerization (SI-ATRP) onto the alkylbromide-modified Fe3O4@SiO2-FITC fluorescent templates, which were synthesized by the co-precipitation of Fe(II) and Fe(III) under basic condition together with the subsequently modified Stöber sol–gel technique. These nanoparticles were characterized by transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), fluorescence spectrum, dynamic light scattering (DLS), and zeta potentials.

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Acknowledgments

This work was supported by the Natural Science Foundation of China (Grant Nos. 21174065, 21374049, and 21344004), PCSIRT (IRT1257), and Tianjin Higher Education Science and Technology Fund Planning Project (Project No. 20110506).

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Authors and Affiliations

  1. Key Laboratory of Functional Polymer Materials, Ministry of Education, Institute of Polymer Chemistry, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Nankai University, Tianjin, 300071, People’s Republic of China

    Tuanwei Liu, Bin Liu, Xiaomeng Fu, Shuxuan Sun & Xinlin Yang

  2. State Key Laboratory of Hollow Fiber Membrane Materials and Processes, School of Environmental and Chemical Engineering, Tianjin Polytechnic University, Tianjin, 300387, People’s Republic of China

    Wei Liu

  3. Dynea Ltd. Co., Gaoyao City, Guangdong, 526105, People’s Republic of China

    Guomin Bian & Yonglin Qi

Authors
  1. Tuanwei Liu
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  2. Bin Liu
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  3. Xiaomeng Fu
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  4. Shuxuan Sun
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  5. Wei Liu
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  6. Guomin Bian
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  7. Yonglin Qi
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  8. Xinlin Yang
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Corresponding authors

Correspondence to Wei Liu or Xinlin Yang.

Additional information

Tuanwei Liu and Bin Liu equally contributed to this work.

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Liu, T., Liu, B., Fu, X. et al. Synthesis of multifunctional microspheres having polymer brush with magnetism, fluorescence, and pH-responsiveness. Colloid Polym Sci 293, 809–816 (2015). https://doi.org/10.1007/s00396-014-3469-4

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  • DOI: https://doi.org/10.1007/s00396-014-3469-4

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