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A multistimuli-responsive supramolecular vesicle constructed by cyclodextrins and tyrosine

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Abstract

Stimuli-responsive vesicle is a significant self-assembly. The supramolecular amphiphile strategy provides a simple way to construct the vesicles. Here, we report a β-cyclodextrin/tyrosine supramolecular vesicle based on host-guest recognition. Tyrosine, which is a nontoxic amino acid, is used as the vesicles building blocks. The β-cyclodextrin/tyrosine vesicles were identified by transmission electron microscopy (TEM), scanning electron microscopy (SEM), and dynamic light scattering (DLS). X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), ultraviolet-visible (UV-vis) spectrum, hydrogen-1 nuclear magnetic resonance (1H NMR), and two-dimensional nuclear magnetic resonance spectroscopy rotating frame nuclear Overhauser effect spectroscopy (2D NMR ROESY) were further employed to elucidate the vesicle formation mechanism. Furthermore, different host molecules, including α-cyclodextrin and γ-cyclodextrin, can all form vesicles with tyrosine. Finally, the vesicles can respond to multiple external stimuli. Competitive guest molecules and copper ions can all disrupt the vesicles’ architectures.

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Authors and Affiliations

  1. School of Chemistry and Chemical Engineering and Key Laboratory of Colloid and Interface Chemistry of Ministry of Education, Shandong University, Jinan, 250100, People’s Republic of China

    Mingfang Ma, Pengyao Xing, Shangyang Li, Xiaoxiao Chu & Aiyou Hao

  2. College of Chemistry and Materials Science, Ludong University, Yantai, 264025, People’s Republic of China

    Shengguang Xu

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  1. Mingfang Ma
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  2. Shengguang Xu
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  3. Pengyao Xing
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  4. Shangyang Li
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  5. Xiaoxiao Chu
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  6. Aiyou Hao
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Correspondence to Aiyou Hao.

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Ma, M., Xu, S., Xing, P. et al. A multistimuli-responsive supramolecular vesicle constructed by cyclodextrins and tyrosine. Colloid Polym Sci 293, 891–900 (2015). https://doi.org/10.1007/s00396-014-3424-4

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  • DOI: https://doi.org/10.1007/s00396-014-3424-4

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