Skip to main content
SpringerLink
Log in

Left atrial appendage closure in a patient with atrial fibrillation after mechanical mitral valve replacement and cardio-embolic stroke despite effective oral anticoagulant therapy: a case report

  • Letter to the Editors
  • Published:
Clinical Research in Cardiology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. (1998) Transesophageal echocardiographic correlates of thromboembolism in high-risk patients with nonvalvular atrial fibrillation. The Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography. Ann Intern Med 128(8):639–647

  2. Camm AJ, Kirchhof P, Lip GY, Schotten U, Savelieva I, Ernst S, Van Gelder IC, Al-Attar N, Hindricks G, Prendergast B, Heidbuchel H, Alfieri O, Angelini A, Atar D, Colonna P, De CR, De SJ, Goette A, Gorenek B, Heldal M, Hohloser SH, Kolh P, Le Heuzey JY, Ponikowski P, Rutten FH (2010) Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Eur Heart J 31(19):2369–2429

    Article  PubMed  Google Scholar 

  3. Ferro JM (2003) Cardioembolic stroke: an update. Lancet Neurol 2(3):177–188

    Article  PubMed  Google Scholar 

  4. Bernhardt P, Schmidt H, Hammerstingl C, Luderitz B, Omran H (2005) Patients with atrial fibrillation and dense spontaneous echo contrast at high risk a prospective and serial follow-up over 12 months with transesophageal echocardiography and cerebral magnetic resonance imaging. J Am Coll Cardiol 45(11):1807–1812

    Article  PubMed  Google Scholar 

  5. Blackshear JL, Odell JA (1996) Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation. Ann Thorac Surg 61(2):755–759

    Article  CAS  PubMed  Google Scholar 

  6. Holmes DR, Reddy VY, Turi ZG, Doshi SK, Sievert H, Buchbinder M, Mullin CM, Sick P (2009) Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial. Lancet 374(9689):534–542

    Article  CAS  PubMed  Google Scholar 

  7. Eikelboom JW, Connolly SJ, Brueckmann M, Granger CB, Kappetein AP, Mack MJ, Blatchford J, Devenny K, Friedman J, Guiver K, Harper R, Khder Y, Lobmeyer MT, Maas H, Voigt JU, Simoons ML, Van de Werf F (2013) Dabigatran versus Warfarin in Patients with Mechanical Heart Valves. N Engl J Med 369(13):1206–1214

    Article  CAS  PubMed  Google Scholar 

  8. Russo A, Grigioni F, Avierinos JF, Freeman WK, Suri R, Michelena H, Brown R, Sundt TM, Enriquez-Sarano M (2008) Thromboembolic complications after surgical correction of mitral regurgitation incidence, predictors, and clinical implications. J Am Coll Cardiol 51(12):1203–1211

    Article  PubMed  Google Scholar 

  9. Bando K, Kobayashi J, Hirata M, Satoh T, Niwaya K, Tagusari O, Nakatani S, Yagihara T, Kitamura S (2003) Early and late stroke after mitral valve replacement with a mechanical prosthesis: risk factor analysis of a 24-year experience. J Thorac Cardiovasc Surg 126(2):358–364

    Article  PubMed  Google Scholar 

  10. Schroeter MR, Danner BC, Hunlich M, Schillinger W (2013) Uncommon delayed and late complications after percutaneous left atrial appendage closure with Amplatzer Cardiac Plug. Clin Res Cardiol 103(4):285–290

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

There are no conflicts of interest.

Author information

Authors and Affiliations

  1. Med. Klinik und Poliklinik II, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Germany

    Alexander Sedaghat, Georg Nickenig & Christoph Hammerstingl

Authors
  1. Alexander Sedaghat
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Georg Nickenig
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Christoph Hammerstingl
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Christoph Hammerstingl.

Electronic supplementary material

Below is the link to the electronic supplementary material.

392_2014_704_MOESM1_ESM.avi

Video 1: Intraprocedural 3D-TEE imaging after successful LAAc showing both the Amplatzer™ left atrial appendage occluder and the mechanical mitral valve (AVI 1660 kb)

392_2014_704_MOESM2_ESM.avi

Video 2: Intraprocedural TEE Doppler imaging after successful LAAc revealing the absence of residual peri-device blood flow (AVI 4463 kb)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sedaghat, A., Nickenig, G. & Hammerstingl, C. Left atrial appendage closure in a patient with atrial fibrillation after mechanical mitral valve replacement and cardio-embolic stroke despite effective oral anticoagulant therapy: a case report. Clin Res Cardiol 103, 587–589 (2014). https://doi.org/10.1007/s00392-014-0704-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00392-014-0704-4

Keywords

Search

Navigation