International Journal of Colorectal Disease

, Volume 25, Issue 4, pp 443–447

Colonoscopy screening for individuals aged 40–49 years with a family history of stomach cancer in Korea


    • Department of GastroenterologyDaehang Hospital
  • Jung Pil Suh
    • Department of GastroenterologyDaehang Hospital
  • Doo Seok Lee
    • Department of SurgeryDaehang Hospital
  • Eui Gon Youk
    • Department of SurgeryDaehang Hospital
  • In Taek Lee
    • Department of SurgeryDaehang Hospital
  • Suk Hee Lee
    • Department of PathologyDaehang Hospital
  • Do Sun Kim
    • Department of SurgeryDaehang Hospital
  • Doo Han Lee
    • Department of SurgeryDaehang Hospital
Original Article

DOI: 10.1007/s00384-009-0855-3

Cite this article as:
Choi, Y.S., Suh, J.P., Lee, D.S. et al. Int J Colorectal Dis (2010) 25: 443. doi:10.1007/s00384-009-0855-3



For asymptomatic individuals aged 40–49 years, screening for colorectal cancer is recommended only if individuals are at an increased risk. A family history of colon cancer (FHCRC) is considered to increase risk, however, whether family history of stomach cancer (FHSC) increases the risk of adenoma is not well known. We aimed to see whether FHSC increases the risk in asymptomatic individuals aged 40–49 years in Korea.


Among asymptomatic individual aged 40–49 years who underwent colonoscopy screening, risk of adenoma was assessed according to FHCRC or FHSC.


Of 3,160 individuals, male comprised 1,602 individuals (50.7%). FHCRC and FHSC was noticed in 163 (5.2%) and 227 (7.0%) individuals, respectively. Prevalence of adenoma was 31.9 %, 28.8%, and 22.3% for individuals with FHCRC, individuals with FHSC, and individuals without family history of cancer, respectively. FHSC was an independent risk factor for adenoma (odds ratio, 1.38; 95% confidence interval, 1.02–1.87, P = 0.039) in asymptomatic individuals aged 40–49 years. Compared with individuals with FHCRC, individuals with FHSC showed no difference in risk for adenoma (P = 0.347).


As with individuals with FHCRC, individuals with FHSC might need to be considered as an individual with increased risk for adenoma. Therefore, earlier screening might be needed for asymptomatic individuals aged 40–49 years with FHSC in Korea.


AdenomaScreeningFamily history of stomach cancer

Copyright information

© Springer-Verlag 2009