Journal of Comparative Physiology A

, Volume 196, Issue 2, pp 155–164

Distress call-induced gene expression in the brain of the Indian short-nosed fruit bat, Cynopterus sphinx

Authors

  • Ambigapathy Ganesh
    • Department of Animal Science, School of Life SciencesBharathidasan University
  • Hanumanthan Raghuram
    • Centre for Ecological Sciences, Indian Institute of Science
  • Parthasarathy T. Nathan
    • Department of Animal Behavior and Physiology, School of Biological SciencesMadurai Kamaraj University
  • Ganapathy Marimuthu
    • Department of Animal Behavior and Physiology, School of Biological SciencesMadurai Kamaraj University
    • Department of Animal Science, School of Life SciencesBharathidasan University
Original Paper

DOI: 10.1007/s00359-009-0502-z

Cite this article as:
Ganesh, A., Raghuram, H., Nathan, P.T. et al. J Comp Physiol A (2010) 196: 155. doi:10.1007/s00359-009-0502-z

Abstract

Individuals in distress emit audible vocalizations to either warn or inform conspecifics. The Indian short-nosed fruit bat, Cynopterus sphinx, emits distress calls soon after becoming entangled in mist nets, which appear to attract conspecifics. Phase I of these distress calls is longer and louder, and includes a secondary peak, compared to phase II. Activity-dependent expression of egr-1 was examined in free-ranging C. sphinx following the emissions and responses to a distress call. We found that the level of expression of egr-1 was higher in bats that emitted a distress call, in adults that responded, and in pups than in silent bats. Up-regulated cDNA was amplified to identify the target gene (TOE1) of the protein Egr-1. The observed expression pattern Toe1 was similar to that of egr-1. These findings suggest that the neuronal activity related to recognition of a distress call and an auditory feedback mechanism induces the expression of Egr-1. Co-expression of egr-1 with Toe1 may play a role in initial triggering of the genetic mechanism that could be involved in the consolidation or stabilization of distress call memories.

Keywords

Distress callChiropteraCynopterus sphinxegr-1Toe1

Abbreviations

IEG

Immediate-early gene

Egr-1

Early growth response 1 gene

TOE1

Target of Egr1

PN

Postnatal day

RT–PCR

Reverse transcriptase-polymerase chain reaction

Copyright information

© Springer-Verlag 2010