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Producing ORMOSIL scaffolds by femtosecond laser polymerization

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Abstract

Structures with different geometries and sizes were built via direct femtosecond laser writing, starting from new organic/inorganic hybrid monomers based on hybrid methacrylate containing triethoxysilane, in addition to urethane and urea groups. Multifunctional oligomer of urethane dimethacrylate type was chosen as comonomer in polymerization experiments because dimethacrylates give rise to the formation of a polymer network, having a number of favorable properties including biocompatibility and surface nanostructuring. Free standing polymeric structures were designed and created in order to be tested in fibroblast cells culture. Investigations of the cellular adhesion, proliferation, and viability of L929 mouse fibroblasts on free-standing laser processed scaffolds were performed for different scaffold designs.

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Acknowledgements

Two authors (Andreea Matei and Tinca Buruiana) acknowledge the financial support of European Social Fund–“Cristofor I. Simionescu” Postdoctoral Fellowship Programme (ID POSDRU/89/1.5/S/55216), Sectoral Operational Programme Human Resources Development 2007–2013.

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Correspondence to M. Dinescu.

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Matei, A., Zamfirescu, M., Radu, C. et al. Producing ORMOSIL scaffolds by femtosecond laser polymerization. Appl. Phys. A 108, 91–97 (2012). https://doi.org/10.1007/s00339-012-7010-7

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  • DOI: https://doi.org/10.1007/s00339-012-7010-7

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