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Embolisation of prostatic arteries as treatment of moderate to severe lower urinary symptoms (LUTS) secondary to benign hyperplasia: results of short- and mid-term follow-up

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An Erratum to this article was published on 20 July 2013

Abstract

Objectives

To evaluate the short- and medium-term results of prostatic arterial embolisation (PAE) for benign prostatic hyperplasia (BPH).

Methods

This was a prospective non-randomised study including 255 patients diagnosed with BPH and moderate to severe lower urinary tract symptoms after failure of medical treatment for at least 6 months. The patients underwent PAE between March 2009 and April 2012. Technical success is when selective prostatic arterial embolisation is completed in at least one pelvic side. Clinical success was defined as improving symptoms and quality of life. Evaluation was performed before PAE and at 1, 3, 6 and every 6 months thereafter with the International Prostate Symptom Score (IPSS), quality of life (QoL), International Index of Erectile Function (IIEF), uroflowmetry, prostatic specific antigen (PSA) and volume. Non-spherical polyvinyl alcohol particles were used.

Results

PAE was technically successful in 250 patients (97.9 %). Mean follow-up, in 238 patients, was 10 months (range 1–36). Cumulative rates of clinical success were 81.9 %, 80.7 %, 77.9 %, 75.2 %, 72.0 %, 72.0 %, 72.0 % and 72.0 % at 1, 3, 6, 12, 18, 24, 30 and 36 months, respectively. There was one major complication.

Conclusions

PAE is a procedure with good results for BPH patients with moderate to severe LUTS after failure of medical therapy.

Key Points

Prostatic artery embolisation offers minimally invasive therapy for benign prostatic hyperplasia.

Prostatic artery embolisation is a challenging procedure because of vascular anatomical variations.

PAE is a promising new technique that has shown good results.

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Abbreviations

BPH:

benign prostatic hyperplasia

PAE:

prostatic artery embolisation

References

  1. Levy A, Samraj GP (2007) Benign prostatic hyperplasia: when to ‘watch and wait’, when and how to treat. Cleve Clin J Med 74:S15–S20

    Article  PubMed  Google Scholar 

  2. Garraway WM, Collins GN, Lee RJ (1991) High prevalence of benign prostatic hypertrophy in the community. Lancet 338:469–471

    Article  PubMed  CAS  Google Scholar 

  3. Michel MC, Mehlburger L, Bressel HU, Schumacher H, Schäfers RF, Goepel M (1998) Tamsulosin treatment of 19,365 patients with lower urinary tract symptoms: does co-morbidity alter tolerability? J Urol 160:784–791

    Article  PubMed  CAS  Google Scholar 

  4. McConnell JD, Bruskewitz R, Walsh P et al (1998) The effect of finasteride on the risk of acute urinary retention and the need for surgical treatment among men with benign prostatic hyperplasia. Finasteride Long-Term Efficacy and Safety Study Group. N Engl J Med 338:557–563

    Article  PubMed  CAS  Google Scholar 

  5. Varkarakis J, Bartsch G, Horninger W (2004) Long-term morbidity and mortality of transurethral prostatectomy: a 10-year follow-up. Prostate 58:248–251

    Article  PubMed  Google Scholar 

  6. Roehrborn CG, Rosen RC (2008) Medical therapy options for aging men with benign prostatic hyperplasia: focus on alfuzosin 10 mg once daily. Clin Interv Aging 3:511–524

    PubMed  CAS  Google Scholar 

  7. Burnett AL, Wein AJ (2006) Benign prostatic hyperplasia in primary care: what you need to know. J Urol 175:S19–S24

    Article  PubMed  Google Scholar 

  8. Baazeem A, Elhilali MM (2008) Surgical management of benign prostatic hyperplasia: current evidence. Nat Clin Pract Urol 5:540–549

    Article  PubMed  Google Scholar 

  9. Reich O, Gratzke C, Bachman A et al (2008) Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective multicenter evaluation of 10,654 patients. J Urol 180:246–249

    Article  PubMed  Google Scholar 

  10. Madersbacher S, Marberger M (1999) Is transurethral resection of the prostate still justified? BJU Int 83:227–237

    Article  PubMed  CAS  Google Scholar 

  11. DeMeritt JS, Elmasri FF, Esposito MP, Rosenberg GS (2000) Relief of benign prostatic hyperplasia-related bladder outlet obstruction after transarterial polyvinyl alcohol prostate embolization. J Vasc Interv Radiol 11:767–770

    Article  PubMed  CAS  Google Scholar 

  12. Carnevale FC, Antunes AA, da Motta Leal Filho JM et al (2010) Prostatic artery embolization as a primary treatment for benign prostatic hyperplasia: preliminary results in two patients. Cardiovasc Intervent Radiol 33:355–361

    Article  PubMed  Google Scholar 

  13. Pisco JM, Pinheiro LC, Bilhim T, Duarte M, Mendes JR, Oliveira AG (2011) Prostatic arterial embolization to treat benign prostatic hyperplasia. J Vasc Interv Radiol 22:11–19

    Article  PubMed  Google Scholar 

  14. Sun F, Sánchez FM, Crisóstomo V et al (2008) Benign prostatic hyperplasia: transcatheter arterial embolization as potential treatment—preliminary study in pigs. Radiology 246:783–789

    Article  PubMed  Google Scholar 

  15. Jeon GS, Won JH, Lee BM et al (2009) The effect of transarterial prostate embolization in hormone-induced benign prostatic hyperplasia in dogs: a pilot study. J Vasc Interv Radiol 20:384–390

    Article  PubMed  Google Scholar 

  16. Mauro MA (2008) Can hyperplastic prostate follow uterine fibroids and be managed with transcatheter arterial embolization? Radiology 246:657–658

    Article  PubMed  Google Scholar 

  17. Bilhim T, Casal D, Furtado A, Pais D, O’Neill JE, Pisco JM (2011) Branching patterns of the male internal iliac artery: imaging findings. Surg Radiol Anat 33:151–159

    Article  PubMed  Google Scholar 

  18. Bilhim T, Pisco JM, Furtado A et al (2011) Prostatic arterial supply: demonstration by multirow detector angio CT and catheter angiography. Eur Radiol 21:1119–1126

    Article  PubMed  Google Scholar 

  19. Sapoval M, Daroles J, Rio Tinto H et al (2012) C-arm cone-beam CT in BPH: techniques and considerations for the safe treatment of benign prostatic hyperplasia. Endovascular Today April:61–63

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Conflict of interest

There is no funding or potential conflicts of interest for the authors regarding this article. The corresponding authors confirm that they have full access to all the data in this study and have final responsibility for the decision to submit for publication. All authors had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

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Correspondence to Hugo Rio Tinto.

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Pisco, J.M., Rio Tinto, H., Campos Pinheiro, L. et al. Embolisation of prostatic arteries as treatment of moderate to severe lower urinary symptoms (LUTS) secondary to benign hyperplasia: results of short- and mid-term follow-up. Eur Radiol 23, 2561–2572 (2013). https://doi.org/10.1007/s00330-012-2714-9

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  • DOI: https://doi.org/10.1007/s00330-012-2714-9

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