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Obesity among women may increase the risk of arthritis: observations from the Canadian Community Health Survey, 2007–2008

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Abstract

Cross-sectional data from the 2007 to 2008 Canadian Community Health Survey were used to investigate the joint effect of obesity and female on the prevalence of arthritis. A total of 94,758 subjects (44,282 men and 50,476 women) aged 18 years or over who answered the question concerning arthritis were included, and sampling weights and design effects were taken into account in the analysis. The prevalence of arthritis among obese (body mass index ≥30 kg/m2) men was 18.0 % and 29.8 % among obese women. The adjusted prevalence ratio for obesity associated with arthritis was 1.45 (95 % confidence interval 1.39, 1.52) for women and 1.38 (confidence interval 1.29, 1.47) for men. The combined effect of obesity and female sex was more than additivity, with the relative excess risk due to the interaction being 0.21 (95 % confidence interval 0.09, 0.32). Obesity is likely to have a larger effect on women with arthritis than men.

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References

  1. Statistics Canada (2012) Arthritis, by sex, and by province and territory. http://www.statcan.gc.ca/tables-tableaux/sum-som/l01/cst01/health52a-eng.htm. Accessed 5 June 2012

  2. Badley E, Wang P (1998) Arthritis and the aging population: projections of arthritis prevalence in Canada 1991 to 2031. J Rheumatol 25:138–144

    PubMed  CAS  Google Scholar 

  3. Canada Health (2003) Arthritis in Canada. An ongoing challenge. Health Canada, Ottawa

    Google Scholar 

  4. Li X, Gignac MA, Anis AH (2006) The indirect costs of arthritis resulting from unemployment, reduced performance, and occupational changes while at work. Med Care 44:304–310

    Article  PubMed  Google Scholar 

  5. Hartz AJ, Fischer ME, Bril G et al (1986) The association of obesity with joint pain and osteoarthritis in the HANES data. J Chronic Dis 39:311–319

    Article  PubMed  CAS  Google Scholar 

  6. Gross AF, Fickert S, Günther KP (2005) Obesity and arthritis. Orthopade 34:638–644

    Article  PubMed  Google Scholar 

  7. Griffen TM, Guilak F (2005) The role of mechanical loading in the onset and progression of osteoarthritis. Exerc Sport Sci Rev 33:195–200

    Article  Google Scholar 

  8. Leveille SG, Wee CC, Iezzoni LI (2005) Trends in obesity and arthritis among baby boomers and their predecessors, 1971–2002. Am J Public Health 95:1607–1613

    Article  PubMed  Google Scholar 

  9. Wearing SC, Hennig EM, Byrne NM, Steele JR, Hills AP (2006) Musculoskeletal disorders associated with obesity: a biomechanical perspective. Obes Rev 7:239–250

    Article  PubMed  CAS  Google Scholar 

  10. Brady TJ, Sniezek JE (2003) Implementing the national arthritis action plan: new population-based approaches to increasing physical activity among people with arthritis. Arthritis Rheum 49:471–476

    Article  PubMed  Google Scholar 

  11. Wareham N, van Sluijs EMF, Ekelund U (2005) Physical activity and obesity prevention: a review of the current evidence. Proc Nutr Soc 64:229–247

    Article  PubMed  Google Scholar 

  12. Anderson JJ, Felson DT (1988) Factors associated with osteoarthritis of knee in the first national health and nutrition examination survey (HANES I): evidence from an association with overweight, race, and physical demands of work. Am J Epidemiol 128:179–189

    PubMed  CAS  Google Scholar 

  13. Soltani-Arabshahi R, Wong B, Feng BJ, Goldgar DE, Duffin KC et al (2010) Obesity in early adulthood as a risk factor for psoriatic arthritis. Arch Dermatol 146:721–726

    Article  PubMed  Google Scholar 

  14. Magliano M (2008) Obesity and arthritis. Menopause Int 14:149–154

    Article  PubMed  Google Scholar 

  15. World Health Organization (2012) Health topic: obesity. http://www.who.int/topics/obesity/en/. Accessed 5 June 2011

  16. Public Health Agency of Canada (2012) Life with Arthritis in Canada: a personal and public health challenge. http://www.phac-aspc.gc.ca/cd-mc/arthritis-arthrite/lwaic-vaaac-10/3-eng.php#What. Accessed 5 June 2011

  17. Jebb SA, Moore MS (1999) Contribution of a sedentary lifestyle and inactivity to the etiology of overweight and obesity: current evidence and research issues. Med Sci Sports Exerc 31:S534–S541

    Article  PubMed  CAS  Google Scholar 

  18. Amin S, Niu J, Guermazi A et al (2007) Cigarette smoking and the risk for cartilage loss and knee pain in men with knee osteoarthritis. Ann Rheum Dis 66:18–22

    Article  PubMed  CAS  Google Scholar 

  19. John U, Hanke M, Rumpf HF, Thyrian JR (2005) Smoking status, cigarettes per day, and their relationship to overweight and obesity among former and current smokers in a national adult general population sample. Int J Obes (Lond) 29:1289–1294

    Article  CAS  Google Scholar 

  20. Chen Y, Dales R, Krewski D, Breithaupt (1999) Increased effects of smoking and obesity on asthma among female Canadian: the national population health survey, 1994–1995. Am J Epidemiol 150:255–262

    Article  PubMed  CAS  Google Scholar 

  21. Andersson T, Alfredsson L, Kallberg H, Zdravkovic S, Ahlbom AC (2005) Calculating measures of biological interaction. Eur J Epidemiol 20:575–579

    Article  PubMed  Google Scholar 

  22. Hosmer DW, Lemeshow S (1992) Confidence interval estimation of interaction. Epidemiology 3:452–456

    Article  PubMed  CAS  Google Scholar 

  23. Cooper C, Snow S, McAlindon TE et al (2000) Risk factors for the incidence and progression of radiographic knee osteoarthritis. Arthritis Rheum 43:995–1000

    Article  PubMed  CAS  Google Scholar 

  24. Song J, Chang RW, Dunlop DD (2006) Population impact of arthritis on disability in older adults. Arthritis Care Res 55:248–255

    Article  Google Scholar 

  25. Mehrotra C, Chudy N, Thomas V (2003) Obesity and physical inactivity among Wisconsin adults with arthritis. Wis Med J 102(7):24–28

    Google Scholar 

  26. Hootman JM, Murhpy LB, Helmick CG (2011) Arthritis as a potential barrier to physical activity among adults with obesity—United States, 2007 and 2009. MMWR Morb Mortal Wkly Rep 60:614–618

    Google Scholar 

  27. Hart DJ, Doyle DV, Spector TD (1999) Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: the Chingford study. Arthritis Rheum 42:17–24

    Article  PubMed  CAS  Google Scholar 

  28. Felson DT, Anderson JJ, Naimark A, Walker AM, Meenan RF (1988) Obesity and knee osteoarthritis. The Framingham Study. Ann Intern Med 109:18–24

    Article  PubMed  CAS  Google Scholar 

  29. Centers for Disease Control and Prevention (1994) Arthritis prevalence and activity limitations: United States, 1990. JAMA 272:346–347

    Article  Google Scholar 

  30. Coggon D, Reading I, Croft P, McLaren M, Barrett D et al (2001) Knee osteoarthritis and obesity. Int J Obes Relat Metab Disord 25:622–627

    Article  PubMed  CAS  Google Scholar 

  31. Sandmark H, Hogstedt C, Lewold S, Vingard E (1999) Osteoarthrosis of the knee in men and women in association with overweight, smoking, and hormone therapy. Ann Rheum Dis 58:151–155

    Article  PubMed  CAS  Google Scholar 

  32. Spector TD, Cicuttini F, Baker J, Loughlin J, Hart D (1996) Genetic influences on osteoarthritis in women: a twin study. BMJ 312:940–943

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

The data set was provided by Statistics Canada. This research was financially supported by the University of Ottawa Graduate Scholarship.

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Correspondence to Gino De Angelis.

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De Angelis, G., Chen, Y. Obesity among women may increase the risk of arthritis: observations from the Canadian Community Health Survey, 2007–2008. Rheumatol Int 33, 2249–2253 (2013). https://doi.org/10.1007/s00296-013-2712-5

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  • DOI: https://doi.org/10.1007/s00296-013-2712-5

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