Abstract
Rheumatoid-like deformities in joints are uncommon in patients with Parkinson’s disease and easy to be misdiagnosed with rheumatoid arthritis. Therefore, unnecessary treatment is often initiated. Here, we report a case of a 60-year-old woman with Parkinson’s disease developing a rheumatoid-like joint deformities, and evaluate 1-year follow-up outcome. We also review the literature and discuss the clinical characteristics, possible pathogenesis, and treatment strategy of these cases.
References
Charcot JM (1877) Lectures on the diseases of the nervous system, lecture V. New Sydenham Society, London, pp 140–147
Fahn S, Oakes D, Shoulson I, Kieburtz K, Rudolph A, Lang A, Olanow CW, Tanner C, Marek K, Parkinson Study Group (2004) Levodopa and the progression of Parkinson’s disease. N Engl J Med 351:2498–2508
Hanly JG, Mosher D, Sutton E, Weerasinghe S, Theriault D (1996) Self-assessment of disease activity by patient with rheumatoid arthritis. J Rheumatol 23:1531–1538
Gortvai P (1963) Deformities of the hand and feet in Parkinsonism and their reversibility by operation. J Neurol Neurosurg Psychiatry 26:33–36
Reynolds FW, Petropoulous GC (1965) Hand deformities in Parkinsonism. J Chronic Dis 18:593–595
Heinzelmann PR, Dow RW (1985) Clawhand deformity presumed secondary to Parkinson’s disease. J Hand Surg Am 10:19–21
Bissonnette B (1986) Pseudorheumatoid deformity of the feet associated with parkinsonism [letter]. J Rheumatol 13:825–826
Harris ED (1987) Pseudorheumatoid deformity of the feet associated with parkinsonism [letter]. Bissonnette B [reply]. J Rheumatol 14:855–856
Kyriakides T, Hewer RL (1988) Hand contractures in Parkinson’s disease. J Neurol Neurosurg Psychiatry 51:1221–1223
Uhrin Z, Stein H (1998) Rheumatoid-like deformities in Parkinson’s disease. J Rheumatol 25:177–179
Hu MT, Bland J, Clough C, Ellis CM, Chaudhuri KR (1999) Limb contractures in levodopa-responsive Parkinsonism: a clinical and investigational study of seven new cases. J Neurol 246:671–676
Aydoğ E, Ekşioğlu E, Cakci A, Yilmaz O (2005) Hand deformity in Parkinson’s disease: case report. Rheumatol Int 25:548–549
Ashour R, Jankovic J (2006) Joint and skeletal deformities in Parkinson’s disease, multiple system atrophy, and progressive supranuclear palsy. Mov Disord 21:1856–1863
Melikoglu MA, Sezer I, Kacar C (2007) Rheumatoid-like hand deformities in Parkinson disease. J Clin Rheumatol 13:236–237
Ashour R, Tintner R, Jankovic J (2005) Striatal deformities of the hand and foot in Parkinson’s disease. Lancet Neurol 4:423–431
Cordivari C, Misra VP, Catania S, Lees AJ (2001) Treatment of dystonic clenched fist with botulinum toxin. Mov Disord 16:907–913
Acknowledgments
We thank Professor Jie Luo for providing pathological picture. We also thank the patient who donated pictures and information to perform the study.
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Shu, X., Wang, G., Lu, X. et al. Rheumatoid-like deformities in Parkinson’s disease with 1-year follow-up: case report and literature review. Rheumatol Int 30, 1493–1497 (2010). https://doi.org/10.1007/s00296-009-1094-1
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DOI: https://doi.org/10.1007/s00296-009-1094-1