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Dermatomyositis, complicated with pneumomediastinum, successfully treated with cyclosporine A: a case report and review of literature

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Abstract

We report a rare case of patient with dermatomyositis (DM) who developed spontaneous pneumomediastinum (PnM) and subcutaneous emphysema. She was successfully treated with oral prednisolone and cyclosporine A (CsA). We reviewed the cases of PnM in patients with DM treated with CsA. A review of four previously reported cases revealed that treatment with systemic glucocorticoid and CsA was effective for the DM and PnM. We indicate that initial and early treatment of the patients with DM and PnM with CsA enabled rapid tapering of the dose of glucocorticoid and improved the disease.

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Authors and Affiliations

  1. Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, #634-18, Geum-Am Dong, Deock-Jin Gu, Jeonju, Jeononbuk, 561-712, South Korea

    Hui-Jung Kim, Yun-Kyung Hong & Wan-Hee Yoo

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  1. Hui-Jung Kim
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  2. Yun-Kyung Hong
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Correspondence to Wan-Hee Yoo.

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Kim, HJ., Hong, YK. & Yoo, WH. Dermatomyositis, complicated with pneumomediastinum, successfully treated with cyclosporine A: a case report and review of literature. Rheumatol Int 29, 1101–1104 (2009). https://doi.org/10.1007/s00296-008-0822-2

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