, Volume 59, Issue 4, pp 167-169
Date: 22 Sep 2013

Yeast membranes and cell wall: from basics to applications

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The surfaces of cells and organelles are crucial territories whose proper structure and function are essential for all cellular activities. In Saccharomyces cerevisiae, the cell envelope alone (plasma membrane and cell wall) occupies about 15 % of the total cell volume (Feldmann 2010). After adding in the membranes of the mitochondria, nuclei, vacuoles, peroxisomes, endoplasmic reticulum and Golgi apparatus as well as a monolayer covering the surface of lipid particles, there is very little room left for the cytosol or organellar matrices. The cell and organellar surfaces sense the environment, relay this information to the interior via signal transduction pathways, mediate (or prevent) the entry of chemicals, excrete toxic substances, enable an uneven distribution of ions thus generating ion and pH gradients that are the driving forces for essential cell processes. Yeast cell surfaces also facilitate the communication of a cell with its neighbors, and, in a yeast pathogen, interact w ...

Communicated by S. Hohmann.
Special Issue: Yeast membranes and cell wall: From basics to applications