Skip to main content
Log in

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Lucchesi M, Guidi M, Fonte C, Farina S, Fiorini P, Favre C, de Martino M, Sardi I (2016) Pharmacokinetics of high-dose methotrexate in infants aged less than 12 months treated for aggressive brain tumors. Cancer Chemother Pharmacol 77:857–864

    Article  CAS  PubMed  Google Scholar 

  2. Morse M, Savitch J, Balis F, Miser J, Feusner J, Reaman G, Poplack D, Bleyer A (1985) Altered central nervous system pharmacology of methotrexate in childhood leukemia: another sign of meningeal relapse. J Clin Oncol 3:19–24

    CAS  PubMed  Google Scholar 

  3. Csordas K, Hegyi M, Eipel OT, Muller J, Erdelyi DJ, Kovacs GT (2013) Comparison of pharmacokinetics and toxicity after high-dose methotrexate treatments in children with acute lymphoblastic leukemia. Anticancer Drugs 24:189–197

    Article  CAS  PubMed  Google Scholar 

  4. Borsi JD, Wesenberg F, Stokland T, Moe PJ (1991) How much is too much? Folinic acid rescue dose in children with acute lymphoblastic leukaemia. Eur J Cancer 27:1006–1009

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Maurizio Lucchesi.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lucchesi, M., Sardi, I. Reply to Prof Ian J. Cohen. Cancer Chemother Pharmacol 78, 219–220 (2016). https://doi.org/10.1007/s00280-016-3061-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00280-016-3061-3

Keywords

Navigation