, Volume 91, Issue 8, pp 1315-1316
Date: 13 Dec 2011

No association between Agent Orange exposure and monoclonal gammopathies

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Dear Editor,

Agent Orange was an herbicide defoliant that was sprayed extensively during Vietnam War by US military forces [1]. It was composed of a 1:1 mixture of 2,4-dichlorophenoxyacetic acid and 2,4,5-tricholorophenoxyacetic acid; the latter was contaminated with 2,3,7,8-tetracholorodibenzo-p-dioxin, also referred to as dioxin [2]. Dioxin has been considered as a one of the most toxic and oncogenic human-made chemicals. [3]. After the war ended, many veterans began to develop an array of health problems. This prompted the US Department of Veterans Affairs and other US governmental organizations, such as the Institute of Medicine and the National Academy of Science (NAS) in collaboration with the Centers for Disease Control and Prevention, to conduct research studies on possible health effects of Agent Orange exposure on US veterans [4]. The diseases that the US Department of Veterans Affairs currently associates with Agent Orange exposure include the following: acute and subacute pe