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Intra-arterial Ultra-low-Dose CT Angiography of Lower Extremity in Diabetic Patients

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Abstract

Purpose

To image lower extremity arteries by CT angiography using a very low-dose intra-arterial contrast medium in patients with high risk of developing contrast-induced nephropathy (CIN).

Materials and Methods

Three cases with long-standing diabetes mellitus and signs of lower extremity atherosclerotic disease were evaluated by CT angiography using 0.1 ml/kg of the body weight of contrast medium given via 10-cm-long 4F introducer by puncturing the CFA. Images were evaluated by an interventional radiologist and a cardiovascular surgeon. Density values of the lower extremity arteries were also calculated. Findings in two cases were compared with digital subtraction angiography images performed for percutaneous revascularization. Blood creatinine levels were followed for possible CIN.

Results

Intra-arterial CT angiography images were considered diagnostic in all patients and optimal in one patient. No patient developed CIN after intra-arterial CT angiography, while one patient developed CIN after percutaneous intervention.

Conclusion

Intra-arterial CT angiography of lower extremity might be performed in selected patients with high risk of developing CIN. Our limited experience suggests that as low as of 0.1 ml/kg of the body weight of contrast medium may result in adequate diagnostic imaging.

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Authors and Affiliations

  1. Department of Radiology, Yeditepe University Hospital, İçerenköy mahallesi, Hastane yolu sokak, No: 102-104, 34752, Ataşehir, İstanbul, Turkey

    Ali Özgen

  2. Department of Cardiovascular Surgery, Yeditepe University Hospital, İçerenköy mahallesi, Hastane yolu sokak, No: 102-104, 34752, Ataşehir, İstanbul, Turkey

    Soner Sanioğlu

  3. Department of Plastic Surgery, Yeditepe University Hospital, İçerenköy mahallesi, Hastane yolu sokak, No: 102-104, 34752, Ataşehir, İstanbul, Turkey

    Uğur Anıl Bingöl

Authors
  1. Ali Özgen
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  2. Soner Sanioğlu
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  3. Uğur Anıl Bingöl
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Correspondence to Ali Özgen.

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There is no conflict of interest or any financial support.

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Informed consent was obtained from all individual participants included in the study.

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Özgen, A., Sanioğlu, S. & Bingöl, U.A. Intra-arterial Ultra-low-Dose CT Angiography of Lower Extremity in Diabetic Patients. Cardiovasc Intervent Radiol 39, 1165–1169 (2016). https://doi.org/10.1007/s00270-016-1358-6

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  • DOI: https://doi.org/10.1007/s00270-016-1358-6

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