An Alternative Therapy for HCC with Portal Vein Tumor Thrombosis: Y-90 Radioembolization
To the Editor,
We read the article Surgical resection versus conformal radiotherapy combined with TACE for resectable hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT): a comparative study by Tang et al.  with great interest. This article will be a useful guide for physicians in the future. In that paper, the authors suggested three-dimensional conformal radiotherapy (3D-CRT) is more useful than surgery in patients with hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). This study showed that the overall survival of patients was better with 3D-CRT than with surgery.
The authors compared only two alternative therapies for HCC: surgery and 3D-CRT. In addition to these therapies, transarterial radioembolization with yttrium-90 (Y-90) microspheres has also been used for these cases, which avoids many of the limitations of external techniques . In our institution, we also perform Y-90 radioembolization in cases of HCC with PVTT.
- Tang, QH, Li, AJ, Yang, GM, Lai, EC, Zhou, WP, Jiang, ZH, Lau, WY, Wu, MC (2013) Surgical resection versus conformal radiotherapy combined with TACE for resectable hepatocellular carcinoma with portal vein tumor thrombus: a comparative study. World J Surg 37: pp. 1362-1370 CrossRef
- Lewandowski, RJ, Salem, R (2006) Yttrium-90 radioembolization of hepatocellular carcinoma and metastatic disease to the liver. Semin Interv Radiol 23: pp. 64-72 CrossRef
- An Alternative Therapy for HCC with Portal Vein Tumor Thrombosis: Y-90 Radioembolization
World Journal of Surgery
Volume 38, Issue 5 , p 1246
- Cover Date
- Print ISSN
- Online ISSN
- Springer US
- Additional Links
- Industry Sectors