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Survival of Minced Cartilage Grafts with Comparison Surgicel® Original and Fibrillar

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Abstract

Background

Cartilage grafts are commonly used in nasal surgery for structural and/or esthetic purposes. The viability of cartilage grafts has been investigated in many forms since the use of cartilage grafts in surgical procedures.

Objectives

The objective of this study was to investigate the viability of minced cartilage grafts and whether there is a difference between grafts wrapped in Surgicel® Original and Surgicel Fibrillar.

Methods

A total of ten New Zealand rabbits were used for the study. Cartilage grafts were harvested from one side ear. Four groups were formed. Group 1: minced cartilage graft wrapped in Surgicel Fibrillar; Group 2: minced cartilage graft wrapped in Surgicel Original; Group 3: bare minced cartilage graft; and Group 4: bare diced cartilage graft. Four small subcutaneous pockets were made in the backs of the rabbits, and the grafts were placed in these pockets. All of the rabbits were sacrificed at the end of 3 months, and the samples were collected. The sections were stained with hematoxylin and eosin (H&E), toluidin blue, safranin-O, masson trichrome, and glial fibrillary acidic protein immunohistochemical. All specimens were assessed histopathologically under a light microscope.

Results

There was no statistically significant difference between the Surgicel Fibrillar and Surgicel Original groups with respect to any of the parameters. Bone formation, calcification, inflammation, fibrosis, and basophilia were similar in all groups, with no significant difference among them. In the Surgicel Fibrillar and Surgicel Original groups, a heavy chondrocyte nucleus loss accompanied by a minimal peripheral proliferation was observed.

Conclusions

The viability of bare minced cartilage grafts was found to be similar to that of bare diced cartilage in this study. Minced cartilage grafts can be used in the correction of minor dorsal defects and irregularities in persons with thin nasal skins, especially in primary and revision rhinoplasty. Although there is no statistically significant difference between the Surgicel Fibrillary and Surgicel Original groups, we think that, if it is necessary to use oxidized regenerated cellulose, it should be in the fibrillar form.

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Authors and Affiliations

  1. Department of Plastic, Reconstructive and Aesthetic Surgery, Pamukkale University Hospital, Denizli, 20070, Pamukkale, Turkey

    Adem Özkan, Adem Topkara & Ramazan Hakan Özcan

  2. Department of Pathology, Pamukkale University Hospital, Denizli, Turkey

    Metin Akbulut

Authors
  1. Adem Özkan
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  2. Adem Topkara
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  3. Metin Akbulut
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  4. Ramazan Hakan Özcan
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Correspondence to Adem Özkan.

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The authors declare that they have no conflict of interest to disclose.

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Özkan, A., Topkara, A., Akbulut, M. et al. Survival of Minced Cartilage Grafts with Comparison Surgicel® Original and Fibrillar. Aesth Plast Surg 40, 602–612 (2016). https://doi.org/10.1007/s00266-016-0661-6

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  • DOI: https://doi.org/10.1007/s00266-016-0661-6

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